SCHEMBL448903

SCHEMBL448903

CO[Si](OC)(OCS)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.32
ALDH1A1 P00352 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31
IDO1 P14902 1/20 0.31
CA4 P22748 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2108822 0.84 HDAC3 (0.33) POLB
SCHEMBL729776 0.81 HDAC3 (0.39)
SCHEMBL1225533 0.81 TSHR (0.33) POLBALDH1A1CA4KDM4EMAPK1
SCHEMBL728489 0.80 HDAC3 (0.46)
SCHEMBL37986 0.79 CA4 (0.41) POLBALDH1A1CYP1A2CYP2C19CA4
SCHEMBL1971501 0.79 POLB (0.32) POLBALDH1A1CA4KDM4EMAPK1
SCHEMBL445218 0.79 POLB (0.32) POLBALDH1A1CA4KDM4EMAPK1
SCHEMBL2201675 0.79 MGAM (0.33) POLBALDH1A1CA4KDM4EMAPK1
SCHEMBL241495 0.79 POLB (0.32) POLBALDH1A1CA4KDM4EMAPK1
SCHEMBL31338421 0.79 POLB (0.32) POLBALDH1A1CA4KDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3733756-B1 TREAD RUBBER COMPOSITION FOR STUDLESS WINTER TIRES SUMITOMO RUBBER IND (JP) 2026-01-28 EP disclosed
CN-120192705-A Aqueous urethane resin composition, coating agent, and article DIC株式会社 2025-06-24 CN disclosed
CN-110540679-B Rubber composition for tire and pneumatic tire 住友橡胶工业株式会社 2023-03-31 CN disclosed
CN-110540687-B Rubber composition for tire and pneumatic tire 住友橡胶工业株式会社 2023-03-10 CN disclosed
US-11433705-B2 Studless tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2022-09-06 US disclosed
CN-110382609-B Studless tire 住友橡胶工业株式会社 2022-03-22 CN disclosed
US-11267285-B2 Rubber composition for tires and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2022-03-08 US disclosed
US-20200391550-A1 TREAD RUBBER COMPOSITION FOR STUDLESS WINTER TIRES SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2020-12-17 US disclosed
CN-107108911-B Method for producing vulcanized rubber composition, and studless tire using same 住友橡胶工业株式会社 2020-11-10 CN disclosed
EP-3733756-A1 TREAD RUBBER COMPOSITION FOR STUDLESS WINTER TIRES SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2020-11-04 EP disclosed
EP-2098554-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER, AND RUBBER COMPOSITION JSR Corporation (JP) 2009-09-09 EP disclosed
US-20080188613-A1 Process For Producing Modified Polymer, Modified Polymer Obtained By The Process, And Rubber Composition Thereof JSR CORPORATION (JP) 2008-08-07 US disclosed
EP-1932869-A1 PROCESS FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER OBTAINED BY THE PROCESS, AND RUBBER COMPOSITION CONTAINING THE SAME JSR Corporation (JP) 2008-06-18 EP disclosed
EP-1479698-B1 Method for producing modified conjugated diene polymer and rubber composition JSR CORP (JP) 2008-05-14 EP disclosed
EP-1860136-A1 PROCESS FOR PRODUCING MODIFIED POLYMER, MODIFIED POLYMER OBTAINED BY THE PROCESS, AND RUBBER COMPOSITION THEREOF JSR Corporation (JP) 2007-11-28 EP disclosed
EP-1777243-A1 AQUEOUS DISPERSIONS OF CATIONIC POLYURETHANE RESINS, INK-JET RECEIVING AGENTS CONTAINING THE SAME, AND INK-JET RECORDING MEDIA MADE BY USING THE AGENTS DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-04-25 EP disclosed
US-7202306-B2 Method for producing modified conjugated diene polymer and rubber composition JSR CORPORATION (JP) 2007-04-10 US disclosed
US-20060264560-A1 Method for producing modified conjugated diene polymer and rubber composition JSR CORPORATION (JP) 2006-11-23 US disclosed
US-20050009979-A1 Method for producing modified conjugated diene polymer and rubber composition JSR CORPORATION (JP) 2005-01-13 US disclosed
EP-1479698-A1 Method for producing modified conjugated diene polymer and rubber composition JSR Corporation (JP) 2004-11-24 EP disclosed