SCHEMBL1225533

SCHEMBL1225533

CCO[Si](OC)(OC)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
POLB P06746 1/20 0.33
LTA4H P09960 1/20 0.33
TP53 P04637 2/20 0.32
CA4 P22748 1/20 0.32
ALDH1A1 P00352 3/20 0.32
MAPK1 P28482 2/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
KDM4E B2RXH2 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
RELA Q04206 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL474158 0.96 TSHR (0.33) TSHRPOLBLTA4HTP53CA4
SCHEMBL2874122 0.94 TSHR (0.33) TSHRPOLBLTA4HTP53CA4
SCHEMBL29900 0.89 LTA4H (0.37) TSHRLTA4HTP53ALDH1A1MAPK1
SCHEMBL8639721 0.89 NQO1 (0.31) ESR1
SCHEMBL28264117 0.88 TSHR (0.30) TSHR
SCHEMBL21060842 0.88 ESR1 (0.32) TSHRPOLBLTA4HTP53CA4
SCHEMBL10566882 0.87 LTA4H (0.36) LTA4HCA4KDM4ESMN1; SMN2RELA
SCHEMBL3295425 0.87 LMNA (0.33) LTA4HALDH1A1HPGD
SCHEMBL8415484 0.86 LTA4H (0.35) TSHRLTA4HTP53ALDH1A1MAPK1
SCHEMBL10495731 0.86 LTA4H (0.35) TSHRLTA4HTP53CA4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117603470-A Core-shell structure polymer silicon dioxide-based conductive microsphere and preparation method thereof 浙江福莱新材料股份有限公司 2024-02-27 CN claimed
CN-112142660-B Method for simply, conveniently and efficiently synthesizing 4-aryl butyric acid derivative 淮阴师范学院 2021-11-23 CN claimed
US-11059920-B2 Process for producing high cis-1,4-polydiene with lanthanide-based catalyst compositions BRIDGESTONE CORPORATION (JP) 2021-07-13 US claimed
EP-3830020-A1 METHODS AND COMPOSITIONS FOR ENHANCED DISPERSION OF PHOSPHOR IN A POLYMERIC MATRIX Board of Regents, The University of Texas System (US) 2021-06-09 EP claimed
CN-111944331-A Surface modification treatment method of anti-settling boron carbide powder 上海核工程研究设计院有限公司 2020-11-17 CN claimed
WO-2020223644-A1 METHODS AND COMPOSITIONS FOR SYNTHESIS OF PHOSPHOR AND ITS INCORPORATION IN A POLYMER MATRIX FOR LIGHT CONVERSION SOLGRO, INC. (US) 2020-11-05 WO claimed
WO-2020028889-A1 METHODS AND COMPOSITIONS FOR ENHANCED DISPERSION OF PHOSPHOR IN A POLYMERIC MATRIX BOARDS OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2020-02-06 WO claimed
US-20190169330-A1 Process For Producing High Cis-1,4-Polydiene With Lanthanide-Based Catalyst Compositions BRIDGESTONE CORPORATION (JP) 2019-06-06 US claimed
EP-3491030-A1 PROCESS FOR PRODUCING HIGH CIS-1,4-POLYDIENE WITH LANTHANIDE-BASED CATALYST COMPOSITIONS Bridgestone Corporation (JP) 2019-06-05 EP claimed
WO-2018022994-A1 PROCESS FOR PRODUCING HIGH CIS-1,4-POLYDIENE WITH LANTHANIDE-BASED CATALYST COMPOSITIONS BRIDGESTONE CORPORATION (JP) 2018-02-01 WO claimed
US-9546237-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2017-01-17 US claimed
CN-102361901-B Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MAT INC 2014-06-11 CN claimed
CN-102361901-A Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MAT INC 2012-02-22 CN claimed
US-4030813-A Control element having liquid layer attainable to geometrically uneven state in response to electrical signal MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JA) 1977-06-21 US claimed
EP-3864059-B1 MODIFIED DIENE COPOLYMERS WITH TARGETED AND STABILIZED VISCOSITY FIRESTONE POLYMERS LLC (US) 2026-01-14 EP disclosed
US-20250179221-A1 HIGHLY FUNCTIONALIZED STABLE HYDROCARBYLOXYSILYL POLYDIENES AND POLYDIENE COPOLYMERS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2025-06-05 US disclosed
US-20250092168-A1 HIGHLY FUNCTIONALIZED STABLE DIHYDROCARBYLOXYSILYL POLYDIENES AND POLYDIENE COPOLYMERS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2025-03-20 US disclosed
US-4626556-A LADDER POLYMERS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1986-12-02 US disclosed
EP-0076656-A2 Solvent-soluble organopolysilsesquioxanes, processes for producing the same, and compositions and semiconductor devices using the same JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-04-13 EP disclosed
US-4030813-A Control element having liquid layer attainable to geometrically uneven state in response to electrical signal MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JA) 1977-06-21 US disclosed