Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4890195 | 0.98 | — | — | |
| SCHEMBL4495865 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL3158142 | 0.69 | — | — | |
| SCHEMBL2868189 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL4489263 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL311809 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL6386343 | 0.66 | — | — | |
| SCHEMBL4890200 | 0.66 | — | — | |
| SCHEMBL6385818 | 0.64 | NPC1 (0.30) | — | |
| SCHEMBL6385816 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046842-A2 | ISOTACTIC-ATACTIC POLYPROPYLENE AND METHODS OF MAKING SAME | Fina Technology, Inc. (US) | 2009-04-15 | — | — | EP | disclosed |
| US-7470759-B2 | Isotactic-atactic polypropylene and methods of making same | FINA TECHNOLOGY, INC. (US) | 2008-12-30 | — | — | US | disclosed |
| WO-2008016904-A2 | ISOTACTIC-ATACTIC POLYPROPYLENE AND METHODS OF MAKING SAME | FINA TECHNOLOGY, INC. (US) | 2008-02-07 | — | — | WO | disclosed |
| US-20080027193-A1 | ISOTACTIC-ATACTIC POLYPROPYLENE AND METHODS OF MAKING SAME | FINA TECHNOLOGY, INC. (US) | 2008-01-31 | — | — | US | disclosed |