Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1461670 | 0.91 | GSK3B (0.82) | GSK3BCYP1A2 | |
| SCHEMBL4487680 | 0.90 | GSK3B (0.84) | GSK3BCYP1A2 | |
| SCHEMBL4483590 | 0.89 | GSK3B (0.84) | GSK3BCYP1A2 | |
| SCHEMBL4503195 | 0.88 | GSK3B (0.73) | GSK3BCYP1A2 | |
| SCHEMBL4497413 | 0.86 | HDAC1 (0.73) | GSK3B | |
| SCHEMBL4488991 | 0.86 | GSK3B (0.85) | GSK3BCYP1A2 | |
| SCHEMBL4499397 | 0.85 | GSK3B (0.70) | GSK3B | |
| SCHEMBL4483435 | 0.84 | GSK3B (0.72) | GSK3B | |
| SCHEMBL4484280 | 0.84 | AAK1 (0.80) | GSK3B | |
| SCHEMBL4486435 | 0.83 | GSK3B (0.85) | GSK3BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7632854-B2 | Aminoindazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them | PFIZER ITALIA S.R.L. (IT) | 2009-12-15 | — | — | US | claimed |