SCHEMBL449018

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL447714	1.00	HSP90AA1 (0.55)	HSP90AA1HSP90AB1MEN1KMT2ACYP1A2
	SCHEMBL464655	0.89	HSP90AA1 (0.68)	HSP90AA1HSP90AB1MEN1KMT2ACYP3A4
	SCHEMBL2476616	0.86	HSP90AA1 (0.52)	HSP90AA1HSP90AB1MEN1KMT2ACYP1A2
	SCHEMBL446362	0.83	HSP90AA1 (0.63)	HSP90AA1HSP90AB1MEN1KMT2AALDH1A1
	SCHEMBL445761	0.83	HSP90AA1 (0.59)	HSP90AA1HSP90AB1KMT2AHTTNPC1
	SCHEMBL445596	0.83	HSP90AA1 (0.59)	HSP90AA1HSP90AB1MEN1KMT2ACYP1A2
	SCHEMBL2476428	0.83	HSP90AA1 (0.53)	HSP90AA1HSP90AB1ALDH1A1MAPT
	SCHEMBL451123	0.81	HSP90AA1 (0.50)	HSP90AA1HSP90AB1MEN1KMT2ACYP1A2
	SCHEMBL447290	0.81	HSP90AA1 (0.51)	HSP90AA1HSP90AB1MEN1KMT2ACYP1A2
	SCHEMBL446749	0.81	HSP90AA1 (0.59)	HSP90AA1HSP90AB1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.