Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL448162 | 0.91 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL449986 | 0.90 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL454849 | 0.88 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL448160 | 0.86 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL451091 | 0.86 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL453808 | 0.86 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL450403 | 0.86 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL449985 | 0.84 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL450535 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4ESMN1; SMN2HPGD | |
| SCHEMBL450437 | 0.83 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1MAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748440-B2 | Quinazolinone modulators of nuclear receptors | EXELIXIS, INC. (US) | 2014-06-10 | — | — | US | claimed |
| US-20120064025-A1 | Quinazolinone Modulators Of Nuclear Receptors | EXELIXIS, INC. (US) | 2012-03-15 | — | — | US | claimed |
| EP-1521746-B1 | QUINAZOLINONE MODULATORS OF NUCLEAR RECEPTORS | X CEPTOR THERAPEUTICS INC (US) | 2011-04-27 | — | — | EP | claimed |
| US-20080070864-A1 | Quinazolinone Modulators Of Nuclear Receptors | X-CEPTOR THERAPEUTICS, INC. (US) | 2008-03-20 | — | — | US | claimed |
| US-20240040853-A1 | DISPLAY PANELS, MANUFACTURING METHODS THEREOF, AND DISPLAY DEVICES | TCL CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) | 2024-02-01 | — | — | US | disclosed |
| EP-4312481-A1 | DISPLAY PANELS, MANUFACTURING METHODS THEREOF, AND DISPLAY DEVICES | TCL CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) | 2024-01-31 | — | — | EP | disclosed |
| US-10665812-B2 | Organic EL display panel and method for producing organic EL display panel | JOLED INC. (JP) | 2020-05-26 | — | — | US | disclosed |
| US-10263046-B2 | Organic EL display panel and method of manufacturing organic EL display panel | JOLED INC. (JP) | 2019-04-16 | — | — | US | disclosed |
| US-20180090546-A1 | ORGANIC EL DISPLAY PANEL AND METHOD OF MANUFACTURING ORGANIC EL DISPLAY PANEL | MAGNOLIA BLUE CORPORATION (JP) | 2018-03-29 | — | — | US | disclosed |
| US-9490444-B2 | Organic light-emitting element with regulation insulating layer and two-component electron transport layer and method of making | JOLED INC. (JP) | 2016-11-08 | — | — | US | disclosed |
| US-9490445-B2 | Organic el element, organic el panel, organic el light-emitting apparatus, organic el display apparatus, and method of manufacturing organic el element | JOLED INC. (JP) | 2016-11-08 | — | — | US | disclosed |
| US-9324964-B2 | Organic light-emitting element with hole injection layer having concave portion | JOLED INC. (JP) | 2016-04-26 | — | — | US | disclosed |
| US-20130126840-A1 | ORGANIC EL ELEMENT, ORGANIC EL PANEL, ORGANIC EL LIGHT-EMITTING APPARATUS, ORGANIC EL DISPLAY APPARATUS, AND METHOD OF MANUFACTURING ORGANIC EL ELEMENT | PANASONIC CORPORATION (JP) | 2013-05-23 | — | — | US | disclosed |
| US-20130105780-A1 | METHOD FOR PRODUCING ORGANIC EL ELEMENT, DISPLAY DEVICE, LIGHT-EMITTING APPARATUS, AND ULTRAVIOLET IRRADIATION DEVICE | PANASONIC CORPORATION (JP) | 2013-05-02 | — | — | US | disclosed |
| US-20130056719-A1 | ORGANIC EL DISPLAY PANEL AND ORGANIC EL DISPLAY APPARATUS | PANASONIC CORPORATION (JP) | 2013-03-07 | — | — | US | disclosed |
| US-20120132934-A1 | ORGANIC EL ELEMENT, DISPLAY APPARATUS, AND LIGHT-EMITTING APPARATUS | PANASONIC CORPORATION (JP) | 2012-05-31 | — | — | US | disclosed |
| US-20120061656-A1 | ORGANIC EL ELEMENT | PANASONIC CORPORATION (JP) | 2012-03-15 | — | — | US | disclosed |
| US-20120064025-A1 | Quinazolinone Modulators Of Nuclear Receptors | EXELIXIS, INC. (US) | 2012-03-15 | — | — | US | disclosed |
| EP-1521746-B1 | QUINAZOLINONE MODULATORS OF NUCLEAR RECEPTORS | X CEPTOR THERAPEUTICS INC (US) | 2011-04-27 | — | — | EP | disclosed |
| US-20080070864-A1 | Quinazolinone Modulators Of Nuclear Receptors | X-CEPTOR THERAPEUTICS, INC. (US) | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120064025-A1 | Quinazolinone Modulators Of Nuclear Receptors | NR1H4, NR1H2, NR1H3 | ALDH1A1 3161/4885L3MBTL1 4767/4885MAPT 4075/4885 |
| US-20080070864-A1 | Quinazolinone Modulators Of Nuclear Receptors | NR1H4, NR1H2, NR1H3 | ALDH1A1 3161/4885L3MBTL1 4767/4885MAPT 4075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.