Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 8/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.45 |
| ▸ | PIM1 | P11309 | 2/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
| ▸ | IP6K1 | Q92551 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240833 | 0.94 | PARP1 (0.49) | PARP1CHEK1PIM1RPS6KA3SLC2A1 | |
| SCHEMBL1011012 | 0.88 | PARP1 (0.50) | PARP1CHEK1PIM1RPS6KA3SLC2A1 | |
| SCHEMBL298221 | 0.85 | PARP1 (0.51) | PARP1CHEK1PIM1RPS6KA3SLC2A1 | |
| SCHEMBL13090419 | 0.84 | PARP1 (0.50) | PARP1CHEK1PIM1RPS6KA3SLC2A1 | |
| SCHEMBL1014333 | 0.82 | SRC (0.55) | PARP1CHEK1PIM1RPS6KA3IP6K1 | |
| SCHEMBL1012421 | 0.82 | SRC (0.55) | PARP1CHEK1PIM1RPS6KA3IP6K1 | |
| SCHEMBL27576840 | 0.81 | SLC2A1 (0.50) | PARP1CHEK1PIM1RPS6KA3SLC2A1 | |
| SCHEMBL4018251 | 0.81 | PARP1 (0.48) | PARP1CHEK1PIM1RPS6KA3SLC2A1 | |
| SCHEMBL3231833 | 0.81 | SLC2A1 (0.47) | PARP1CHEK1PIM1RPS6KA3SLC2A1 | |
| SCHEMBL18655504 | 0.81 | PARP1 (0.50) | PARP1CHEK1PIM1RPS6KA3SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576090-B2 | e.g. N-[2-(6,7-Dimethoxyquinazolin-4-ylamino)benzothiazol-6-yl ]benzamide; multi-target protein kinase, especially epidermal and endothrlial growth factor, inhibitors; antiproliferative, anticarcinogenic agent | 4SC AG (DE) | 2009-08-18 | — | — | US | disclosed |
| US-20060142570-A1 | Benzazole analogues and uses thereof | 4SC AG (DE) | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142570-A1 | Benzazole analogues and uses thereof | CYP3A5, CYP3A7, CYP3A43 | PARP1 1801/4885CHEK1 1877/4885PIM1 652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.