Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.53 |
| ▸ | NR3C2 | P08235 | 15/20 | 0.53 |
| ▸ | PGR | P06401 | 10/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4470861 | 0.89 | NR3C1 (0.66) | NR3C1NR3C2PGR | |
| SCHEMBL4467206 | 0.88 | NR3C1 (0.49) | NR3C1NR3C2PGR | |
| SCHEMBL4485580 | 0.87 | NR3C1 (0.49) | NR3C1NR3C2PGR | |
| SCHEMBL4468476 | 0.79 | NR3C1 (0.53) | NR3C1NR3C2PGR | |
| SCHEMBL4491053 | 0.79 | NR3C1 (0.53) | NR3C1NR3C2PGR | |
| SCHEMBL4469146 | 0.79 | NR3C1 (0.61) | NR3C1NR3C2PGR | |
| SCHEMBL4474870 | 0.78 | NR3C1 (0.51) | NR3C1NR3C2PGR | |
| SCHEMBL4475008 | 0.78 | NR3C1 (0.51) | NR3C1NR3C2PGR | |
| SCHEMBL4474979 | 0.77 | NR3C1 (0.62) | NR3C1NR3C2PGR | |
| SCHEMBL6227820 | 0.77 | NR3C1 (0.54) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579469-B2 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-08-25 | — | — | US | claimed |
| EP-1583745-A1 | 1-PROPANOL AND 1-PROPYLAMINE DERIVATIVES AND THEIR USE AS GLUCOCORTICOID LIGANDS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2005-10-12 | — | — | EP | claimed |
| WO-2004063163-A1 | 1-PROPANOL AND 1-PROPYLAMINE DERIVATIVES AND THEIR USE AS GLUCOCORTICOID LIGANDS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2004-07-29 | — | — | WO | claimed |
| US-7579469-B2 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-08-25 | — | — | US | disclosed |