SCHEMBL449127

SCHEMBL449127

C[Si](C)(C)OC1=CCCC=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbon Monoxide SCHEMBL11903152 0.92
SCHEMBL6412973 0.79 PREP (0.30)
SCHEMBL18137507 0.79
SCHEMBL1683755 0.73
SCHEMBL7540308 0.72
SCHEMBL28080165 0.71
SCHEMBL18469593 0.68
SCHEMBL9647050 0.68
Carbon Monoxide SCHEMBL11902625 0.67
SCHEMBL26796368 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7402689-B2 Vinylchloroformate-free synthesis of vinyl and allyl(thio) carbamates BAUSCH & LOMB INCORPORATED (US) 2008-07-22 US claimed
EP-1892237-A1 Vinylchloroformate-free synthesis of vinyl and allyl(thio)carbamates Bausch & Lomb Incorporated (US) 2008-02-27 EP claimed
EP-1708989-A1 VINYLCHLOROFORMATE-FREE SYNTHESIS OF VINYL AND ALLYL(THIO)CARBAMATES BAUSCH & LOMB INCORPORATED (US) 2006-10-11 EP claimed
WO-2005073181-A1 VINYLCHLOROFORMATE-FREE SYNTHESIS OF VINYL AND ALLYL(THIO)CARBAMATES BAUSCH & LOMB INCORPORATED (US) 2005-08-11 WO claimed
US-20050176980-A1 Vinylchloroformate-free synthesis of vinyl and allyl(thio) carbamates BAUSCH & LOMB INCORPORATED 2005-08-11 US claimed
CN-121586718-A Process for preparing optically active azabicyclo derivatives and intermediates therefor 住友制药株式会社 2026-02-27 CN disclosed
US-20260022205-A1 Polycarbonate Resin, Polycarbonate Resin Composition, Optical Component, and Producing Method for Polycarbonate Resin ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-01-22 US disclosed
WO-2025023321-A1 PROCESS FOR PREPARING OPTICALLY-ACTIVE AZABICYCLO RING DERIVATIVE, AND INTERMEDIATE FOR ITS PRODUCTION Sumitomo Pharma Co., Ltd. (JP) 2025-01-30 WO disclosed
EP-4497771-A1 POLYCARBONATE RESIN, POLYCARBONATE RESIN COMPOSITION, OPTICAL COMPONENT, AND PRODUCTION METHOD FOR POLYCARBONATE RESIN Asahi Kasei Kabushiki Kaisha (JP) 2025-01-29 EP disclosed
CN-118541413-A Polycarbonate resin, polycarbonate resin composition, optical member, and method for producing polycarbonate resin 旭化成株式会社 2024-08-23 CN disclosed
WO-2023182378-A1 POLYCARBONATE RESIN, POLYCARBONATE RESIN COMPOSITION, OPTICAL COMPONENT, AND PRODUCTION METHOD FOR POLYCARBONATE RESIN 旭化成株式会社 2023-09-28 WO disclosed
US-20230212152-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. 2023-07-06 US disclosed
EP-0422596-B1 Tricyclic carbapenem compounds TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1995-07-05 EP disclosed
US-5407931-A Bactericides GLAXO S.P.A. (IT) 1995-04-18 US disclosed
WO-1995006030-A1 HYDROXYETHYLAMINO SULPHONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1995-03-02 WO disclosed
US-5393751-A Antibiotics TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-02-28 US disclosed
US-5138048-A 4-(2-OXO-CYCLOHEXYL) AZETIDINONES GLAXO S.P.A. (IT) 1992-08-11 US disclosed
EP-0422596-A2 Tricyclic carbapenem compounds Takeda Chemical Industries, Ltd. (JP) 1991-04-17 EP disclosed
EP-0416952-A2 4-(1'-Oxocyclohex-2'-yl)azetidin-2-one derivatives GLAXO S.p.A. (IT) 1991-03-13 EP disclosed
EP-0416953-A2 10-(1-Hydroxyethyl)-11-oxo-1-azatricyclo[7.2.0.0.3,8]undec-2-ene-2-carboxylic acid derivatives GLAXO S.p.A. (IT) 1991-03-13 EP disclosed