⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28080165 | 0.97 | — | — | |
| Carbon Monoxide SCHEMBL11902625 | 0.91 | — | — | |
| Ethylamine SCHEMBL27805738 | 0.89 | — | — | |
| Carbon Monoxide SCHEMBL1449984 | 0.84 | — | — | |
| SCHEMBL11902629 | 0.84 | — | — | |
| Propionic Acid SCHEMBL27977704 | 0.82 | FFAR3 (0.36) | — | |
| SCHEMBL7540308 | 0.78 | — | — | |
| SCHEMBL7068841 | 0.76 | — | — | |
| SCHEMBL17531787 | 0.75 | — | — | |
| SCHEMBL449127 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166156-B | Tyrosine kinase inhibitors, compositions and methods | 贝达药业股份有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-110869360-B | Phenylacetamides as ROCK inhibitors | 百时美施贵宝公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-117203198-A | Compounds as PU.1 inhibitors | 浙江星浩澎博医药有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-116472292-A | Modified proteins and protein degrading agents | 上海睿跃生物科技有限公司 | 2023-07-21 | — | — | CN | disclosed |
| US-11571416-B2 | Amodiaquine analogs and methods of uses thereof | KAGOSHIMA UNIVERSITY (JP) | 2023-02-07 | — | — | US | disclosed |
| WO-2022262597-A1 | TNF-α SMALL MOLECULE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 复旦大学 | 2022-12-22 | — | — | WO | disclosed |
| WO-2022219636-A1 | ANTI-VIRAL AND ANTI-TUMORAL COMPOUNDS, AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2022-10-20 | — | — | WO | disclosed |
| EP-4046996-A1 | CRYPTOPHYCIN COMPOUNDS AND CONJUGATES THEREOF | Universität Bielefeld (DE) | 2022-08-24 | — | — | EP | disclosed |
| CN-114805462-A | Steroid derivative regulator and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114656514-A | Steroid derivative regulator and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2022-06-24 | — | — | CN | disclosed |
| EP-1740583-B1 | OXADIAZOLONE DERIVATIVES AS PPAR DELTA AGONISTS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-07-01 | — | — | EP | disclosed |
| WO-2009018169-A1 | SUBSTITUTED CYCLOHEXANOLS | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-02-05 | — | — | WO | disclosed |
| WO-2008141077-A1 | PROCESS FOR THE PREPARATION OF TETRAHYDROQUINOLINYL, BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-11-20 | — | — | WO | disclosed |
| EP-1946777-A1 | Substituted pyrazoline for preventing weight gain | Laboratorios del Dr. Esteve S.A. (ES) | 2008-07-23 | — | — | EP | disclosed |
| WO-2008079427-A1 | 1,2,3,4-TETRAHYDRO-QUINOLINE DERIVATIVES AS CETP INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-07-03 | — | — | WO | disclosed |
| US-20080161187-A1 | Controlling phytopathogenic harmful fungi and harmful arthropodes; combating arthropodal pestsprotecting crops, seeds and non-living materials from infestation by arthropodal pests; insecticides, pesticides, fungicides; miticides; agriculture; veterinary medicine | BASF AKTIENGESELLSCHAFT (DE) | 2008-07-03 | — | — | US | disclosed |
| WO-2007134149-A2 | 3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE AND THIAZINE DERIVATIVES AS CETP INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-11-22 | — | — | WO | disclosed |
| EP-1849783-A1 | Octahydropentalene-substituted pyrazoline compounds, their preparation and use as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-10-31 | — | — | EP | disclosed |
| EP-1832619-A1 | BENZOXAZOLE RESIN PRECURSOR, POLYBENZOXAZOLE RESIN, RESIN FILM, AND SEMICONDUCTOR DEVICE | Sumitomo Bakelite Company, Limited (JP) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006056930-A2 | NOVEL 4 -AMINOPIPERIDINE DERIVATIVES AS PLASMEPSIN II INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-06-01 | — | — | WO | disclosed |