Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 16/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 12/20 | 0.57 |
| ▸ | TP53 | P04637 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | HTT | P42858 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.55 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PKLR | P30613 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4490945 | 0.99 | GAA (0.56) | GAASMN1; SMN2TP53MAPTHTT | |
| SCHEMBL4502584 | 0.81 | GAA (0.58) | GAASMN1; SMN2TP53MAPTHTT | |
| Hydrochloric Acid SCHEMBL4490753 | 0.80 | GAA (0.57) | GAASMN1; SMN2TP53MAPTHTT | |
| SCHEMBL4481573 | 0.80 | GAA (0.59) | GAASMN1; SMN2TP53MAPTHTT | |
| Hydrochloric Acid SCHEMBL4558970 | 0.79 | GAA (0.58) | GAASMN1; SMN2TP53MAPTHTT | |
| SCHEMBL4484626 | 0.79 | GAA (0.60) | GAASMN1; SMN2TP53MAPTHTT | |
| Hydrochloric Acid SCHEMBL4489184 | 0.78 | GAA (0.59) | GAASMN1; SMN2TP53MAPTHTT | |
| SCHEMBL23720420 | 0.68 | ALOX12 (0.48) | GAASMN1; SMN2HTTKMT2AKDM4E | |
| SCHEMBL19352969 | 0.68 | ALOX12 (0.48) | GAASMN1; SMN2HTTKMT2AKDM4E | |
| SCHEMBL4476462 | 0.65 | NR1H4 (0.68) | GAASMN1; SMN2TP53MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592351-B2 | Substituted imidazo[1,2-a]pyridine compounds and pharmaceutical preparations containing substituted imidazo[1,2-a]pyridine compounds | GRUENENTHAL GMBH (DE) | 2009-09-22 | — | — | US | claimed |
| US-20070099896-A1 | Substituted imidazo[1,2-a]pyridine compounds and pharmaceutical preparations containing substituted imidazo[1,2-a]pyridine compounds | GRUENENTHAL GMBH (DE) | 2007-05-03 | — | — | US | claimed |
| EP-1756105-A1 | SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AND DRUGS CONTAINING SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE COMPOUNDS | Grünenthal GmbH (DE) | 2007-02-28 | — | — | EP | claimed |
| WO-2005105798-A1 | SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AND DRUGS CONTAINING SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE COMPOUNDS | Grünenthal GmbH (DE) | 2005-11-10 | — | — | WO | claimed |
| US-7592351-B2 | Substituted imidazo[1,2-a]pyridine compounds and pharmaceutical preparations containing substituted imidazo[1,2-a]pyridine compounds | GRUENENTHAL GMBH (DE) | 2009-09-22 | — | — | US | disclosed |
| US-20070099896-A1 | Substituted imidazo[1,2-a]pyridine compounds and pharmaceutical preparations containing substituted imidazo[1,2-a]pyridine compounds | GRUENENTHAL GMBH (DE) | 2007-05-03 | — | — | US | disclosed |
| EP-1756105-A1 | SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AND DRUGS CONTAINING SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE COMPOUNDS | Grünenthal GmbH (DE) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005105798-A1 | SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AND DRUGS CONTAINING SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE COMPOUNDS | Grünenthal GmbH (DE) | 2005-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099896-A1 | Substituted imidazo[1,2-a]pyridine compounds and pharmaceutical preparations containing substituted imidazo[1,2-a]pyridine compounds | GIPR, CHUK, ITPA | GAA 506/4885SMN1; SMN2 549/4885TP53 456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.