SCHEMBL449164

SCHEMBL449164

[SiH3]O[SiH2]CC1(C2CCCCC2)CO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5129151 0.67 ASGR1 (0.30)
SCHEMBL22497371 0.67
SCHEMBL8105682 0.67 SHBG (0.31)
SCHEMBL10925243 0.60 CHRM5 (0.31)
SCHEMBL9488890 0.58 CHRM2 (0.31)
SCHEMBL29062385 0.57
SCHEMBL4964095 0.57
SCHEMBL4147616 0.55
SCHEMBL8167958 0.55
SCHEMBL2706488 0.54 MAPK1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170096748-A1 CROSSLINKED FIBERS AND METHOD OF MAKING SAME USING UV RADIATION TYCO HEALTHCARE GROUP LP 2017-04-06 US disclosed
US-9523159-B2 Crosslinked fibers and method of making same using UV radiation COVIDIEN LP (US) 2016-12-20 US disclosed
EP-2398943-B1 CROSSLINKED FIBERS AND METHOD OF MAKING SAME USING UV RADIATION SOFRADIM PRODUCTION (FR) 2013-04-17 EP disclosed
US-20120021015-A1 CROSSLINKED FIBERS AND METHOD OF MAKING SAME USING UV RADIATION TYCO HEALTHCARE GROUP LP (US) 2012-01-26 US disclosed
WO-2010095055-A1 CROSSLINKED FIBERS AND METHOD OF MAKING SAME USING UV RADIATION SOFRADIM PRODUCTION (FR) 2010-08-26 WO disclosed