Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 12/20 | 0.73 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.52 |
| ▸ | PTGFR | P43088 | 5/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.52 |
| ▸ | PTGIR | P43119 | 2/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4492407 | 1.00 | PTGER4 (0.73) | PTGER4PTGER3PTGFRPTGER1PTGER2 | |
| SCHEMBL129658 | 0.92 | PTGER4 (0.75) | PTGER4PTGER3PTGFRPTGER1PTGER2 | |
| SCHEMBL129656 | 0.92 | PTGER4 (0.75) | PTGER4PTGER3PTGFRPTGER1PTGER2 | |
| SCHEMBL129657 | 0.92 | PTGER4 (0.75) | PTGER4PTGER3PTGFRPTGER1PTGER2 | |
| SCHEMBL7131273 | 0.92 | PTGER4 (0.75) | PTGER4PTGER3PTGFRPTGER1PTGER2 | |
| SCHEMBL1011637 | 0.91 | PTGER4 (0.68) | PTGER4PTGER3PTGFRPTGER1PTGER2 | |
| SCHEMBL1013598 | 0.91 | PTGER4 (0.68) | PTGER4PTGER3PTGFRPTGER1PTGER2 | |
| SCHEMBL1011832 | 0.88 | PTGER4 (0.73) | PTGER4PTGER3PTGFRPTGER1PTGER2 | |
| SCHEMBL1010823 | 0.88 | PTGER4 (0.73) | PTGER4PTGER3PTGFRPTGER1PTGER2 | |
| SCHEMBL4502745 | 0.88 | PTGER4 (0.67) | PTGER4PTGER3PTGFRPTGER1PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7015243-B2 | Cyclohexyl prostaglandin analogs as EP4-receptor agonists | ALLERGAN, INC. (US) | 2006-03-21 | — | — | US | claimed |
| US-7473704-B2 | Cyclohexyl prostaglandin analogs as EP4-receptor agonists | ALLERGAN, INC. (US) | 2009-01-06 | — | — | US | disclosed |
| US-7473704-B2 | Cyclohexyl prostaglandin analogs as EP4-receptor agonists | ALLERGAN, INC. (US) | 2009-01-06 | — | — | US | disclosed |
| US-7473704-B2 | Cyclohexyl prostaglandin analogs as EP4-receptor agonists | ALLERGAN, INC. (US) | 2009-01-06 | — | — | US | disclosed |
| US-7429615-B2 | Cyclohexyl prostaglandin analogs as EP4-receptor agonists | ALLERGAN, INC. (US) | 2008-09-30 | — | — | US | disclosed |
| US-7429615-B2 | Cyclohexyl prostaglandin analogs as EP4-receptor agonists | ALLERGAN, INC. (US) | 2008-09-30 | — | — | US | disclosed |
| US-7429615-B2 | Cyclohexyl prostaglandin analogs as EP4-receptor agonists | ALLERGAN, INC. (US) | 2008-09-30 | — | — | US | disclosed |
| US-20060247215-A1 | Cyclohexyl prostaglandin analogs as rp4-receptor agonists | OLD DAVID W | 2006-11-02 | — | — | US | disclosed |
| US-7015243-B2 | Cyclohexyl prostaglandin analogs as EP4-receptor agonists | ALLERGAN, INC. (US) | 2006-03-21 | — | — | US | disclosed |
| US-20060030606-A1 | Cyclohexyl prostaglandin analogs as EP4-receptor agonists | ALLERGAN, INC. | 2006-02-09 | — | — | US | disclosed |
| US-20050049227-A1 | Cyclohexyl prostaglandin analogs as EP4-receptor agonists | ALLERGAN, INC. | 2005-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247215-A1 | Cyclohexyl prostaglandin analogs as rp4-receptor agonists | PTGER4, PTGER1, PTGER3 | PTGER4 1/4885PTGER3 3/4885PTGFR 7/4885 |
| US-20060030606-A1 | Cyclohexyl prostaglandin analogs as EP4-receptor agonists | PTGER4, PTGER1, PTGIR | PTGER4 1/4885PTGER3 4/4885PTGFR 7/4885 |
| US-20050049227-A1 | Cyclohexyl prostaglandin analogs as EP4-receptor agonists | PTGER4, PTGER1, PTGIR | PTGER4 1/4885PTGER3 4/4885PTGFR 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.