SCHEMBL4492456

SCHEMBL4492456

Brc1cccc2ccccc12.ICI

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.43
HSD17B10 Q99714 4/20 0.43
CYP2A6 P11509 3/20 0.43
TSHR P16473 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
CYP1A2 P05177 6/20 0.41
CYP2C19 P33261 3/20 0.41
CYP2C9 P11712 2/20 0.41
HPGD P15428 2/20 0.41
CYP3A4 P08684 1/20 0.41
KEAP1 Q14145 1/20 0.41
PRNP P04156 1/20 0.40
HPRT1 P00492 1/20 0.40
POLB P06746 1/20 0.40
PTPN1 P18031 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
CYP2D6 P10635 1/20 0.38
HIF1A Q16665 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69629 0.90 ALDH1A1 (0.53) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL8824112 0.90 ALDH1A1 (0.53) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL29405063 0.90 ALDH1A1 (0.53) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL29903148 0.90 ALDH1A1 (0.53) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Benzene SCHEMBL28694599 0.87 ALDH1A1 (0.50) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Naphthalene SCHEMBL8135433 0.87 ALDH1A1 (0.50) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL9635910 0.87 ALDH1A1 (0.50) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL1248531 0.87 ALDH1A1 (0.50) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL16668580 0.81 CYP1A2 (0.46) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL28601827 0.79 ALDH1A1 (0.42) ALDH1A1HSD17B10CYP2A6TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7588816-B2 Biaxially oriented polyester film for heat-metal lamination MITSUBISHI POLYESTER FILM GMBH (DE) 2009-09-15 US disclosed
US-20070269649-A1 Biaxially oriented polyester film for heat-metal lamination MITSUBISHI POLYESTER FILM GMBH (DE) 2007-11-22 US disclosed
US-7238417-B2 Transparent film made from PET and PEN with UV protection, process for producing the film, and use of the film in packaging with extended shelf life MITSUBISHI POLYESTER FILM GMBH (DE) 2007-07-03 US disclosed
US-7157132-B2 Multilayer, coextrusion, heat setting MITSUBISHI POLYESTER FILM GMBH (DE) 2007-01-02 US disclosed
US-7122240-B2 Multilayer transparent, biaxially oriented polyester film MITSUBISHI POLYESTER FILM GMBH (DE) 2006-10-17 US disclosed
US-7112360-B2 thermoplastic polyester and a pigment system that has a median grain diameter (d50) of 1.5-5 mu m and the spread of the distribution, expressed via the SPAN 98, is less than or equal to 1.9. MITSUBISHI POLYESTER FILM GMBH (DE) 2006-09-26 US disclosed
US-6984437-B2 Multilayer, biaxially oriented polyester film, process for its production and its use MITSUBISHI POLYESTER FILM GMBH (DE) 2006-01-10 US disclosed
US-6881470-B2 Biaxially oriented, co-extruded polyester films comprising a base layer consisting of at least 90 wt. % thermoplastic polyester, preferably polyethylene terephthalate (PET), at least one sealable outer layer and a second non-sealable outer MITSUBISHI POLYESTER FILM GMBH (DE) 2005-04-19 US disclosed
US-6863954-B2 Transparent, sealable, UV-resistant polyester film, its use and process for its production MITSUBISHI POLYESTER FILM GMBH (DE) 2005-03-08 US disclosed
US-6841222-B2 To extend the sealing range of the film to low temperatures, to increase the seal seam strength of the film, and at the same time to provide better handling of the film MITSUBISHI POLYESTER FILM GMBH (DE) 2005-01-11 US disclosed
US-6423401-B2 MULTILAYER; LOW TEMPERATURE SEALING MITSUBISHI POLYESTER FILM GMBH (DE) 2002-07-23 US disclosed
US-6420019-B1 COEXTRUSION OF AT LEAST THREE LAYERS; LOW PLANAR ORIENTATION; PUNCTURE RESISTANT; HIGH GLOSS; LOW HAZE; NONFRAGMENTING; METAL-FREE; YOGHURT CONTAINER LIDS MITSUBISHI POLYESTER FILM GMBH (DE) 2002-07-16 US disclosed
US-20020071945-A1 Transparent, high-gloss plastic films for use in packaging MITSUBISHI POLYESTER FILM GMBH (DE) 2002-06-13 US disclosed
US-20020068159-A1 Matte outer layer of thermoplastic polyester and also to a pigment system with narrow grain size distribution, characteristic optical properties; use as a packaging film MISTUBISHI POLYESTER FILM GMBH (DE) 2002-06-06 US disclosed
US-20020068158-A1 Coextruded, biaxially oriented polyester film having at least one matt side MITSUBISHI POLYESTER FILM GMBH (DE) 2002-06-06 US disclosed
US-20020051872-A1 Comprising ethylene isoterephthalate-ethylene terephthalate copolymer; for use in flexible packaging MITSUBISHI POLYESTER FILM GMBH (DE) 2002-05-02 US disclosed
US-6376042-B1 EXTERIOR LAYER CONTAINING PARTICLES; GAS AND OXYGEN BARRIER MITSUBISHI POLYESTER FILM GMBH (DE) 2002-04-23 US disclosed
US-20020045039-A1 Coextrusion of at least three layers; low planar orientation; puncture resistant; high gloss; low haze; nonfragmenting; metal-free; yoghurt container lids MITSUBISHI POLYESTER FILM GMBH (DE) 2002-04-18 US disclosed
US-20010035593-A1 Multilayer; low temperature sealing MITSUBISHI POLYESTER FILM GMBH (DE) 2001-11-01 US disclosed
US-6261663-B1 BLEND WITH PARTICLES MITSUBISHI POLYSTER FILM GMBH (DE) 2001-07-17 US disclosed