SCHEMBL449304

SCHEMBL449304

CCCCN(N)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.46
TDP1 Q9NUW8 1/20 0.44
AOC3 Q16853 2/20 0.44
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
NPC1 O15118 1/20 0.41
JAK2 O60674 1/20 0.41
RAB9A P51151 1/20 0.41
PAX8 Q06710 1/20 0.41
DHFR P00374 2/20 0.40
TP53 P04637 1/20 0.40
OPRM1 P35372 2/20 0.40
OPRL1 P41146 1/20 0.40
KCNH2 Q12809 2/20 0.39
CHRM2 P08172 1/20 0.39
HTR1A P08908 1/20 0.39
ADRA2A P08913 1/20 0.39
CHRM1 P11229 1/20 0.39
DRD1 P21728 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4056298 0.98 ESR1 (0.45) ESR1TDP1AOC3MEN1KMT2A
SCHEMBL253120 0.94 NPC1 (0.47) ESR1TDP1AOC3NPC1JAK2
SCHEMBL6488829 0.92 NPC1 (0.50) ESR1AOC3NPC1JAK2RAB9A
SCHEMBL6487469 0.92 NPC1 (0.50) ESR1AOC3NPC1JAK2RAB9A
SCHEMBL6477702 0.92 NPC1 (0.50) ESR1AOC3NPC1JAK2RAB9A
SCHEMBL6477185 0.92 NPC1 (0.50) ESR1AOC3NPC1JAK2RAB9A
SCHEMBL6484775 0.92 NPC1 (0.50) ESR1AOC3NPC1JAK2RAB9A
SCHEMBL6485740 0.86 ESR1 (0.43) ESR1TDP1AOC3DHFRTP53
SCHEMBL9717165 0.86 AOC3 (0.45) TDP1AOC3OPRM1KCNH2CHRM2
Hydrochloric Acid SCHEMBL28200131 0.84 ESR1 (0.42) ESR1TDP1AOC3DHFRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114349656-B Preparation method of hydrazide compound 赣南师范大学 2024-03-29 CN claimed
EP-3575101-B1 OPTICAL DEVICE AND STACKED BODY FOR MANUFACTURING THE SAME TOPPAN PRINTING CO LTD (JP) 2025-11-12 EP disclosed
EP-3306362-B2 LAMINATE AND MANUFACTURING METHOD FOR SAME TOPPAN PRINTING CO LTD (JP) 2025-07-02 EP disclosed
CN-116003336-B 1,2, 4-Triazole-3-amine compound, and preparation method and application thereof 赣南师范大学 2024-11-05 CN disclosed
CN-114349656-B Preparation method of hydrazide compound 赣南师范大学 2024-03-29 CN disclosed
CN-110483400-B Preparation method of pyrazole derivative 上海应用技术大学 2023-04-28 CN disclosed
CN-116023335-A Benzoyl urea derivative and preparation method and application thereof 河北科技大学 2023-04-28 CN disclosed
CN-116003336-A 1,2, 4-triazole-3-amine compound, and preparation method and application thereof 赣南师范大学 2023-04-25 CN disclosed
CN-112812040-B Amidine acylhydrazone compound and preparation method thereof 赣南师范大学 2023-03-31 CN disclosed
CN-112859222-B Laminate and method for producing same 凸版印刷株式会社 2022-08-12 CN disclosed
CN-1127487-C Phthalazinones ALTANA PHARMA AG (DE) 2003-11-12 CN disclosed
CN-1425714-A Flame-retardant polyamide or poly resin composition DAIICHI SEIYAKU PHARMACEUTICAL (JP) 2003-06-25 CN disclosed
US-20030114567-A1 Contains 3-50 parts by weight per 100 parts of said resin of brominated polystyrene or brominated polyphenylene ether and thermal coloration inhibitor selected from hydrazine compounds DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2003-06-19 US disclosed
CN-1387517-A 5-aryl-1H-1,2,4-triazole compounds as inhibitors of cyclooxygenase-2 and pharmaceutical compositions contg. them LAB THERAMEX (MC) 2002-12-25 CN disclosed
CN-1249749-A Phthalazinones BYK GULDEN LOMBERC CHEM FAB GM (DE) 2000-04-05 CN disclosed
CN-1249756-A Metallocenes and catalysts for olefin-polymerisation MONTELL TECHNOLOGY COMPANY BV (NL) 2000-04-05 CN disclosed
EP-0034285-B1 PROCESS FOR THE PREPARATION OF 1-ALKYL-1-PHENYL HYDRAZINES HOECHST AKTIENGESELLSCHAFT (DE) 1985-11-06 EP disclosed
EP-0034285-A2 Process for the preparation of 1-alkyl-1-phenyl hydrazines HOECHST AKTIENGESELLSCHAFT (DE) 1981-08-26 EP disclosed
US-3984437-A CATIONIC DIAZAMETHINE; SYNTHETIC FIBERS MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1976-10-05 US disclosed
US-3931215-A OPTICAL BRIGHTENERS HOECHST AKTIENGESELLSCHAFT (DT) 1976-01-06 US disclosed