Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28200131 | 0.98 | ESR1 (0.42) | ESR1TP53AOC3ALDH1A1KDM4E | |
| SCHEMBL449304 | 0.86 | ESR1 (0.46) | ESR1TP53AOC3MAPTTDP1 | |
| SCHEMBL9717180 | 0.85 | AOC3 (0.43) | AOC3ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL253120 | 0.85 | NPC1 (0.47) | ESR1TP53AOC3TDP1CHRM2 | |
| Hydrochloric Acid SCHEMBL4056298 | 0.85 | ESR1 (0.45) | ESR1TP53AOC3TDP1CHRM2 | |
| SCHEMBL6477185 | 0.83 | NPC1 (0.50) | ESR1AOC3OPRM1DRD3KCNH2 | |
| SCHEMBL6477702 | 0.83 | NPC1 (0.50) | ESR1AOC3OPRM1DRD3KCNH2 | |
| SCHEMBL6488829 | 0.83 | NPC1 (0.50) | ESR1AOC3OPRM1DRD3KCNH2 | |
| SCHEMBL6487469 | 0.83 | NPC1 (0.50) | ESR1AOC3OPRM1DRD3KCNH2 | |
| SCHEMBL6484775 | 0.83 | NPC1 (0.50) | ESR1AOC3OPRM1DRD3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114349656-B | Preparation method of hydrazide compound | 赣南师范大学 | 2024-03-29 | — | — | CN | claimed |
| CN-116003336-B | 1,2, 4-Triazole-3-amine compound, and preparation method and application thereof | 赣南师范大学 | 2024-11-05 | — | — | CN | disclosed |
| CN-114349656-B | Preparation method of hydrazide compound | 赣南师范大学 | 2024-03-29 | — | — | CN | disclosed |
| CN-116003336-A | 1,2, 4-triazole-3-amine compound, and preparation method and application thereof | 赣南师范大学 | 2023-04-25 | — | — | CN | disclosed |
| CN-114349656-A | Preparation method of hydrazide compound | 赣南师范大学 | 2022-04-15 | — | — | CN | disclosed |
| CN-107663161-A | A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt | 上海惠和化德生物科技有限公司 | 2018-02-06 | — | — | CN | disclosed |
| CN-103958536-A | Organic tungsten complexes | VANDERBILT CHEMICALS LLC | 2014-07-30 | — | — | CN | disclosed |
| CN-101657461-B | Organic tungsten complexes | VANDERBILT CO R T | 2013-07-17 | — | — | CN | disclosed |
| CN-1817837-B | Carbonyl compound and method for preparing the same | SUMITOMO CHEMICAL CO | 2010-06-16 | — | — | CN | disclosed |
| CN-101657461-A | organic tungsten complexes | VANDERBILT CO R T US | 2010-02-24 | — | — | CN | disclosed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | disclosed |
| EP-1102753-A2 | PYRAZOLES AS ESTROGEN RECEPTOR MODULATORS | CHIRON CORPORATION (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000007996-A2 | PYRAZOLES AS ESTROGEN RECEPTOR MODULATORS | CHIRON CORPORATION (US) | 2000-02-17 | — | — | WO | disclosed |
| CN-1213379-A | Peptide derivatives | ZENECA LTD (GB) | 1999-04-07 | — | — | CN | disclosed |
| US-5225421-A | Leukotriene antagonists; cytoprotective agents | MERCK FROSST CANADA, INC. (CA) | 1993-07-06 | — | — | US | disclosed |
| EP-0034285-B1 | PROCESS FOR THE PREPARATION OF 1-ALKYL-1-PHENYL HYDRAZINES | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-11-06 | — | — | EP | disclosed |
| EP-0034285-A2 | Process for the preparation of 1-alkyl-1-phenyl hydrazines | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-08-26 | — | — | EP | disclosed |
| US-4258059-A | Amino-benzamides | USV PHARMACEUTICAL CORPORATION (US) | 1981-03-24 | — | — | US | disclosed |
| US-3987234-A | ACRYLIC ESTER POLYMERS | HENKEL & CIE G.M.B.H. (DT) | 1976-10-19 | — | — | US | disclosed |
| US-3984437-A | CATIONIC DIAZAMETHINE; SYNTHETIC FIBERS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1976-10-05 | — | — | US | disclosed |