Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4494721 | 0.99 | CYP1A2 (0.43) | CYP1A2CYP3A4HSD17B10KDM4EMAOA | |
| Hydrochloric Acid SCHEMBL4502022 | 0.87 | CYP1A2 (0.47) | CYP1A2CYP3A4HSD17B10KDM4ECYP2D6 | |
| SCHEMBL4496527 | 0.82 | RAD52 (0.61) | KMT2AALDH1A1ACP1RAD52POLB | |
| Hydrochloric Acid SCHEMBL4519576 | 0.81 | KMT2A (0.43) | CYP1A2CYP3A4HSD17B10KDM4EMAOB | |
| SCHEMBL4511938 | 0.79 | MEN1 (0.43) | CYP1A2CYP3A4CYP2D6KMT2ACLK4 | |
| Hydrochloric Acid SCHEMBL4518504 | 0.75 | PDE5A (0.52) | CYP1A2CYP3A4CYP2D6KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL4521126 | 0.74 | KDM4E (0.45) | CYP1A2CYP3A4HSD17B10KDM4EKMT2A | |
| SCHEMBL1289375 | 0.74 | KDM1A (0.54) | CYP1A2CYP3A4HSD17B10KDM4ECYP2D6 | |
| Hydrochloric Acid SCHEMBL4505205 | 0.73 | KDM1A (0.53) | CYP1A2CYP3A4HSD17B10KDM4ECYP2D6 | |
| Hydrochloric Acid SCHEMBL4508477 | 0.71 | PDE5A (0.43) | CYP1A2KMT2AMEN1ALDH1A1PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318479-A1 | SUBSTITUTED RING FUSED AZINES AND THEIR USE IN CANCER THERAPY | AUCKLAND UNISERVICES LIMITED | 2009-12-24 | — | — | US | claimed |
| US-20090318479-A1 | SUBSTITUTED RING FUSED AZINES AND THEIR USE IN CANCER THERAPY | AUCKLAND UNISERVICES LIMITED | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318479-A1 | SUBSTITUTED RING FUSED AZINES AND THEIR USE IN CANCER THERAPY | TP53, AZI2, MCL1 | CYP1A2 1062/4885CYP3A4 1221/4885HSD17B10 3351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.