⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11174303 | 0.91 | CYP2D6 (0.50) | — | |
| SCHEMBL21605353 | 0.81 | — | — | |
| SCHEMBL1275889 | 0.77 | CYP2D6 (0.65) | — | |
| SCHEMBL6850946 | 0.77 | CYP2D6 (0.65) | — | |
| SCHEMBL91326 | 0.74 | — | — | |
| SCHEMBL402167 | 0.74 | — | — | |
| SCHEMBL967152 | 0.74 | — | — | |
| SCHEMBL10447542 | 0.74 | CYP2D6 (0.62) | — | |
| SCHEMBL24253280 | 0.74 | — | — | |
| SCHEMBL14265618 | 0.74 | MAPT (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1487789-A | Selective herbicides based on 2, 6-disubstituted pyridine derivatives | — | 2004-04-07 | — | — | CN | claimed |
| EP-0121076-B1 | PROCESS AND AGENT FOR PRODUCING WEED-FREE PEAT PRODUCTS | Torfstreuverband GmbH (DE) | 1987-06-24 | — | — | EP | claimed |
| US-7612106-B2 | Fused pyrazole derivatives and methods of treatment of metabolic-related disorders thereof | ARENA PHARMACEUTICALS, INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-20090258892-A1 | FUSED PYRAZOLE DERIVATIVES AND METHODS OF TREATMENT OF METABOLIC-RELATED DISORDERS THEREOF | ARENA PHARMACEUTICALS, INC. (US) | 2009-10-15 | — | — | US | disclosed |
| US-7241792-B2 | Fused pyrazole derivatives and methods of treatment of metabolic-related disorders thereof | ARENA PHARMACEUTICALS, INC. (US) | 2007-07-10 | — | — | US | disclosed |
| US-20070073062-A1 | Fused pyrazole derivatives and methods of treatment of metabolic-related disorders thereof | ARENA PHARMACEUTICALS, INC. | 2007-03-29 | — | — | US | disclosed |
| CN-1278607-C | Selective herbicides based on 2, 6-disubstituted pyridine derivatives | BAYER AG (DE) | 2006-10-11 | — | — | CN | disclosed |
| US-20060205955-A1 | Fused pyrazole derivatives and methods of treatment of metabolic-related disorders thereof | ARENA PHARMACEUTICALS, INC. (US) | 2006-09-14 | — | — | US | disclosed |
| CN-1768582-A | Selective herbicides based on 2,6-disubstituted pyridine derivatives | BAYER AG (DE) | 2006-05-10 | — | — | CN | disclosed |
| CN-1487789-A | Selective herbicides based on 2, 6-disubstituted pyridine derivatives | — | 2004-04-07 | — | — | CN | disclosed |
| EP-0251827-B1 | NEW CYCLIC ETHER DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-09-15 | — | — | EP | disclosed |
| US-4891363-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | SANKYO COMPANY LIMITED (JP) | 1990-01-02 | — | — | US | disclosed |
| EP-0251827-A2 | New cyclic ether derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-01-07 | — | — | EP | disclosed |
| EP-0124982-B1 | HERBICIDAL DIPHENYL ETHER DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-05-06 | — | — | EP | disclosed |
| US-4282168-A | FUNGICIDES | PPG INDUSTRIES, INC. (US) | 1981-08-04 | — | — | US | disclosed |
| US-4055657-A | S-ARYL-N-ALKYL-THIOLCARBAMATES | PPG INDUSTRIES, INC. (US) | 1977-10-25 | — | — | US | disclosed |