⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4494378 | 1.00 | — | — | |
| SCHEMBL5513303 | 1.00 | — | — | |
| SCHEMBL11886523 | 1.00 | — | — | |
| SCHEMBL4494386 | 1.00 | — | — | |
| SCHEMBL20624832 | 0.98 | ALDH1A1 (0.41) | — | |
| SCHEMBL2322130 | 0.87 | ALDH1A1 (0.40) | — | |
| SCHEMBL13883684 | 0.85 | ALDH1A1 (0.54) | — | |
| SCHEMBL4476946 | 0.82 | ALDH1A1 (0.56) | — | |
| SCHEMBL4476952 | 0.82 | ALDH1A1 (0.56) | — | |
| SCHEMBL4479334 | 0.82 | ALDH1A1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115023478-A | Polishing composition | 日本瓦姆&珀巴尔株式会社 | 2022-09-06 | — | — | CN | disclosed |
| CN-109824904-B | Modified MQ silicon resin and preparation method and application thereof | 万华化学集团股份有限公司 | 2021-09-03 | — | — | CN | disclosed |
| CN-109824904-A | A kind of modified MQ silicone resin and its preparation method and application | 万华化学集团股份有限公司 | 2019-05-31 | — | — | CN | disclosed |
| US-7612106-B2 | Fused pyrazole derivatives and methods of treatment of metabolic-related disorders thereof | ARENA PHARMACEUTICALS, INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-20090258892-A1 | FUSED PYRAZOLE DERIVATIVES AND METHODS OF TREATMENT OF METABOLIC-RELATED DISORDERS THEREOF | ARENA PHARMACEUTICALS, INC. (US) | 2009-10-15 | — | — | US | disclosed |
| EP-1831178-A2 | FUSED PYRAZOLE DERIVATIVES AND USES THEREOF IN METHODS OF TREATMENT OF METABOLIC-RELATED DISORDERS | Arena Pharmaceuticals, Inc. (US) | 2007-09-12 | — | — | EP | disclosed |
| US-7241792-B2 | Fused pyrazole derivatives and methods of treatment of metabolic-related disorders thereof | ARENA PHARMACEUTICALS, INC. (US) | 2007-07-10 | — | — | US | disclosed |
| US-20070073062-A1 | Fused pyrazole derivatives and methods of treatment of metabolic-related disorders thereof | ARENA PHARMACEUTICALS, INC. | 2007-03-29 | — | — | US | disclosed |
| US-20060205955-A1 | Fused pyrazole derivatives and methods of treatment of metabolic-related disorders thereof | ARENA PHARMACEUTICALS, INC. (US) | 2006-09-14 | — | — | US | disclosed |
| WO-2006069242-A2 | FUSED PYRAZOLE DERIVATIVES AND USES THEREOF IN METHODS OF TREATMENT OF METABOLIC-RELATED?DISORDERS | ARENA PHARMACEUTICALS, INC. (US) | 2006-06-29 | — | — | WO | disclosed |
| CN-1045202-C | Process for making 1,3-diols and 3-hydroxyaldehydes | SHELL INT RESEARCH (NL) | 1999-09-22 | — | — | CN | disclosed |
| EP-0682650-B1 | PROCESS FOR MAKING 1,3-DIOLS AND 3-HYDROXYALDEHYDES | SHELL INT RESEARCH (NL) | 1998-05-20 | — | — | EP | disclosed |
| CN-1117289-A | Process for making 1,3-diols and 3-hydroxyaldehydes | SHELL INT RESEARCH (NL) | 1996-02-21 | — | — | CN | disclosed |
| EP-0682650-A1 | PROCESS FOR MAKING 1,3-DIOLS AND 3-HYDROXYALDEHYDES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1995-11-22 | — | — | EP | disclosed |
| US-5344993-A | Catalytic hydroformylation of epoxides with di-tert-phosphines | SHELL OIL COMPANY (US) | 1994-09-06 | — | — | US | disclosed |
| WO-1994018149-A1 | PROCESS FOR MAKING 1,3-DIOLS AND 3-HYDROXYALDEHYDES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1994-08-18 | — | — | WO | disclosed |
| EP-0263403-B1 | NOVEL MICROORGANISM AND METHOD FOR PRODUCING OXYGENOUS COMPOUNDS WITH SAID MICROORGANISM | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1993-04-21 | — | — | EP | disclosed |
| EP-0263403-A2 | Novel microorganism and method for producing oxygenous compounds with said microorganism | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1988-04-13 | — | — | EP | disclosed |