⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4506840 | 0.89 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL11046955 | 0.88 | — | — | |
| SCHEMBL8977172 | 0.87 | PTAFR (0.39) | — | |
| SCHEMBL11047917 | 0.84 | — | — | |
| SCHEMBL379887 | 0.84 | — | — | |
| SCHEMBL13523730 | 0.76 | — | — | |
| SCHEMBL11639700 | 0.76 | — | — | |
| SCHEMBL19333587 | 0.75 | KDM4E (0.35) | — | |
| SCHEMBL11639533 | 0.73 | MEN1 (0.38) | — | |
| SCHEMBL727275 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7518003-B2 | Production process of tetrahydropyran compound and tetrahydropyran compound produced by the production process | SHOWA DENKO K.K. (JP) | 2009-04-14 | — | — | US | claimed |
| US-20080139828-A1 | Reacting 3,4-dihydro-2-alkoxy-2H-pyran with hydrogen in the presence of a catalyst under acidic condition; Grignard reaction solvent or polymer solvent | SHOWA DENKO K.K. (JP) | 2008-06-12 | — | — | US | claimed |
| EP-1828158-A1 | PRODUCTION PROCESS OF TETRAHYDROPYRAN COMPOUND AND TETRAHYDROPYRAN COMPOUND PRODUCED BY THE PRODUCTION PROCESS | SHOWA DENKO KABUSHIKI KAISHA (JP) | 2007-09-05 | — | — | EP | claimed |
| WO-2006062211-A1 | PRODUCTION PROCESS OF TETRAHYDROPYRAN COMPOUND AND TETRAHYDROPYRAN COMPOUND PRODUCED BY THE PRODUCTION PROCESS | SHOWA DENKO K.K. (JP) | 2006-06-15 | — | — | WO | claimed |
| US-7518003-B2 | Production process of tetrahydropyran compound and tetrahydropyran compound produced by the production process | SHOWA DENKO K.K. (JP) | 2009-04-14 | — | — | US | disclosed |
| US-20080139828-A1 | Reacting 3,4-dihydro-2-alkoxy-2H-pyran with hydrogen in the presence of a catalyst under acidic condition; Grignard reaction solvent or polymer solvent | SHOWA DENKO K.K. (JP) | 2008-06-12 | — | — | US | disclosed |
| EP-1828158-A1 | PRODUCTION PROCESS OF TETRAHYDROPYRAN COMPOUND AND TETRAHYDROPYRAN COMPOUND PRODUCED BY THE PRODUCTION PROCESS | SHOWA DENKO KABUSHIKI KAISHA (JP) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006062211-A1 | PRODUCTION PROCESS OF TETRAHYDROPYRAN COMPOUND AND TETRAHYDROPYRAN COMPOUND PRODUCED BY THE PRODUCTION PROCESS | SHOWA DENKO K.K. (JP) | 2006-06-15 | — | — | WO | disclosed |
| CN-1233610-C | Method for hydrolyzing pyran to prepare glutaraldehyde using heteropolyacid as catalyst | SHANGHAI HUAYI ACRYLIC ACID CO (CN) | 2005-12-28 | — | — | CN | disclosed |
| EP-1072577-B1 | Preparation of pentanediols from alkoxydihydropyrans | BASF AG (DE) | 2005-03-09 | — | — | EP | disclosed |
| CN-1569791-A | Method for hydrolyzing pyran to prepare glutaraldehyde using heteropolyacid as catalyst | SHANGHAI HUAYI ACRYLIC ACID CO (CN) | 2005-01-26 | — | — | CN | disclosed |
| US-6403845-B1 | SINGLE-STEP REACTION OF ALKOXYDIHYDROPYRAN WITH WATER AND HYDROGEN USING A HYDROXYLATION CATALYST COMPRISED OF NICKEL, ZIRCONIUM, COPPER, AND MOLYBDENUM OXIDES; HIGH YIELD | BASF AKTIENGESELLSCHAFT (DE) | 2002-06-11 | — | — | US | disclosed |
| EP-0717026-B1 | Process for the preparation of glutaraldehyde | BASF AG (DE) | 1998-04-08 | — | — | EP | disclosed |
| US-5679868-A | Preparation of glutaric dialdehyde | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-21 | — | — | US | disclosed |
| US-5600018-A | Preparation of glutaraldehyde | BASF AKTIENGESELLSCHAFT (DE) | 1997-02-04 | — | — | US | disclosed |
| EP-0717026-A1 | Process for the preparation of glutaraldehyde | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-19 | — | — | EP | disclosed |
| EP-0697392-A1 | Process for the preparation of glutaraldehyde | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-21 | — | — | EP | disclosed |
| US-5108740-A | Biodegradable films; sustained release | ECOLAB INC. (US) | 1992-04-28 | — | — | US | disclosed |
| US-4908381-A | Tetrahydropyran containing unsaturated ester or amide derivative | ECOLAB INC. (US) | 1990-03-13 | — | — | US | disclosed |
| US-4107289-A | Use of substituted pyrans as deodorant chemicals | NAARDEN INTERNATIONAL HOLLAND, B.V. (NL) | 1978-08-15 | — | — | US | disclosed |