Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTAFR | P25105 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977172 | 0.95 | PTAFR (0.39) | SMN1; SMN2PTAFRGBA1ALDH1A1TDP1 | |
| SCHEMBL4494500 | 0.89 | — | — | |
| SCHEMBL11046955 | 0.85 | — | — | |
| SCHEMBL379887 | 0.81 | — | — | |
| SCHEMBL19333587 | 0.79 | KDM4E (0.35) | ALDH1A1 | |
| SCHEMBL19333597 | 0.74 | — | — | |
| SCHEMBL10143682 | 0.74 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL13523730 | 0.73 | — | — | |
| SCHEMBL4496767 | 0.70 | PPP5C (0.31) | SMN1; SMN2GBA1 | |
| SCHEMBL11639533 | 0.70 | MEN1 (0.38) | PTAFRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7518003-B2 | Production process of tetrahydropyran compound and tetrahydropyran compound produced by the production process | SHOWA DENKO K.K. (JP) | 2009-04-14 | — | — | US | claimed |
| US-20080139828-A1 | Reacting 3,4-dihydro-2-alkoxy-2H-pyran with hydrogen in the presence of a catalyst under acidic condition; Grignard reaction solvent or polymer solvent | SHOWA DENKO K.K. (JP) | 2008-06-12 | — | — | US | claimed |
| EP-1828158-A1 | PRODUCTION PROCESS OF TETRAHYDROPYRAN COMPOUND AND TETRAHYDROPYRAN COMPOUND PRODUCED BY THE PRODUCTION PROCESS | SHOWA DENKO KABUSHIKI KAISHA (JP) | 2007-09-05 | — | — | EP | claimed |
| WO-2006062211-A1 | PRODUCTION PROCESS OF TETRAHYDROPYRAN COMPOUND AND TETRAHYDROPYRAN COMPOUND PRODUCED BY THE PRODUCTION PROCESS | SHOWA DENKO K.K. (JP) | 2006-06-15 | — | — | WO | claimed |
| US-7518003-B2 | Production process of tetrahydropyran compound and tetrahydropyran compound produced by the production process | SHOWA DENKO K.K. (JP) | 2009-04-14 | — | — | US | disclosed |
| US-20080139828-A1 | Reacting 3,4-dihydro-2-alkoxy-2H-pyran with hydrogen in the presence of a catalyst under acidic condition; Grignard reaction solvent or polymer solvent | SHOWA DENKO K.K. (JP) | 2008-06-12 | — | — | US | disclosed |
| CN-101068800-A | Method for producing tetrahydropyran compound and tetrahydropyran compound produced by the production method | SHOWA DENKO KK (JP) | 2007-11-07 | — | — | CN | disclosed |
| EP-1828158-A1 | PRODUCTION PROCESS OF TETRAHYDROPYRAN COMPOUND AND TETRAHYDROPYRAN COMPOUND PRODUCED BY THE PRODUCTION PROCESS | SHOWA DENKO KABUSHIKI KAISHA (JP) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006062211-A1 | PRODUCTION PROCESS OF TETRAHYDROPYRAN COMPOUND AND TETRAHYDROPYRAN COMPOUND PRODUCED BY THE PRODUCTION PROCESS | SHOWA DENKO K.K. (JP) | 2006-06-15 | — | — | WO | disclosed |
| CN-1233610-C | Method for hydrolyzing pyran to prepare glutaraldehyde using heteropolyacid as catalyst | SHANGHAI HUAYI ACRYLIC ACID CO (CN) | 2005-12-28 | — | — | CN | disclosed |
| EP-1072577-B1 | Preparation of pentanediols from alkoxydihydropyrans | BASF AG (DE) | 2005-03-09 | — | — | EP | disclosed |
| CN-1569791-A | Method for hydrolyzing pyran to prepare glutaraldehyde using heteropolyacid as catalyst | SHANGHAI HUAYI ACRYLIC ACID CO (CN) | 2005-01-26 | — | — | CN | disclosed |
| EP-1072577-A2 | Preparation of pentanediols from alkoxydihydropyrans | BASF AKTIENGESELLSCHAFT (DE) | 2001-01-31 | — | — | EP | disclosed |
| US-6166225-A | Processes for producing dialdehyde monoacetals | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0987261-A1 | PROCESSES FOR PRODUCING DIALDEHYDE MONOACETALS | DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) | 2000-03-22 | — | — | EP | disclosed |
| EP-0717026-B1 | Process for the preparation of glutaraldehyde | BASF AG (DE) | 1998-04-08 | — | — | EP | disclosed |
| US-5679868-A | Preparation of glutaric dialdehyde | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-21 | — | — | US | disclosed |
| US-5600018-A | Preparation of glutaraldehyde | BASF AKTIENGESELLSCHAFT (DE) | 1997-02-04 | — | — | US | disclosed |
| EP-0717026-A1 | Process for the preparation of glutaraldehyde | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-19 | — | — | EP | disclosed |
| EP-0697392-A1 | Process for the preparation of glutaraldehyde | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139828-A1 | Reacting 3,4-dihydro-2-alkoxy-2H-pyran with hydrogen in the presence of a catalyst under acidic condition; Grignard reaction solvent or polymer solvent | HPD, ACR, GRHPR | SMN1; SMN2 4462/4885PTAFR 1598/4885GBA1 3499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.