Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30932520 | 0.75 | KDM4E (0.39) | ALDH1A1PKMKDM4EGAAMAPT | |
| SCHEMBL30932459 | 0.75 | ALDH1A1 (0.37) | ALDH1A1PKMKDM4EGAAMAPT | |
| SCHEMBL9337322 | 0.75 | CA1 (0.31) | — | |
| SCHEMBL2160895 | 0.71 | POLB (0.30) | — | |
| SCHEMBL5716054 | 0.71 | ALDH1A1 (0.34) | ALDH1A1PKMKDM4EGAAMAPT | |
| SCHEMBL27588107 | 0.71 | — | — | |
| SCHEMBL20816325 | 0.70 | ALDH1A1 (0.50) | ALDH1A1PKMKDM4EGAAMAPT | |
| SCHEMBL8977414 | 0.70 | KDM4E (0.46) | ALDH1A1PKMKDM4EGAAMAPT | |
| SCHEMBL30932472 | 0.68 | KDM4E (0.45) | ALDH1A1PKMKDM4EGAAMAPT | |
| SCHEMBL30932473 | 0.68 | ALDH1A1 (0.33) | ALDH1A1PKMKDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563793-B2 | Pyrrolo[1,2-a]quinoxalin-5-(4H)-yl)sulfonyls and carbonyls and their use as estrogenic agents | WYETH (US) | 2009-07-21 | — | — | US | disclosed |
| US-20060160815-A1 | Pyrrolo[1,2-a]quinoxalin-5-(4H)-yl)sulfonyls and carbonyls and their use as estrogenic agents | WYETH (US) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160815-A1 | Pyrrolo[1,2-a]quinoxalin-5-(4H)-yl)sulfonyls and carbonyls and their use as estrogenic agents | ESR1, GPER1, ESR2 | ALDH1A1 2755/4885PKM 1830/4885KDM4E 90/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.