SCHEMBL1496027

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29449726	0.89	KDM4E (0.73)	KDM4EGAAMAPTIDO1HTT
	SCHEMBL11523761	0.89	KDM4E (0.73)	KDM4EGAAMAPTIDO1HTT
	SCHEMBL4495740	0.89	KDM4E (0.73)	KDM4EGAAMAPTIDO1HTT
	SCHEMBL20336230	0.89	KDM4E (0.73)	KDM4EGAAMAPTIDO1HTT
	SCHEMBL11521138	0.87	KDM4E (0.69)	KDM4EGAAMAPTIDO1HTT
	SCHEMBL23016004	0.80	GAA (0.61)	KDM4EGAAMAPTIDO1KMT2A
	SCHEMBL7634561	0.80	GAA (0.61)	KDM4EGAAMAPTIDO1KMT2A
	SCHEMBL21392344	0.78	KDM4E (0.58)	KDM4EGAAMAPTIDO1SMN1; SMN2
	SCHEMBL13801654	0.78	KDM4E (0.58)	KDM4EGAAMAPTIDO1HTT
	SCHEMBL3691601	0.77	MAPT (0.58)	KDM4EGAAMAPTIDO1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.