Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4480912 | 0.80 | — | — | |
| SCHEMBL8573447 | 0.70 | ALDH1A1 (0.39) | HSD17B10 | |
| SCHEMBL1009054 | 0.70 | ALDH1A1 (0.39) | HSD17B10 | |
| SCHEMBL29150788 | 0.68 | ALDH1A1 (0.37) | HSD17B10 | |
| SCHEMBL16950065 | 0.67 | KDM4E (0.35) | HSD17B10 | |
| SCHEMBL16731961 | 0.67 | USP2 (0.38) | USP2 | |
| SCHEMBL14989322 | 0.66 | ALDH1A1 (0.36) | HSD17B10 | |
| SCHEMBL6014064 | 0.66 | ALDH1A1 (0.36) | HSD17B10 | |
| SCHEMBL29614893 | 0.66 | ALDH1A1 (0.36) | HSD17B10 | |
| SCHEMBL13343473 | 0.66 | ALDH1A1 (0.36) | USP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504429-B2 | Tyrosine kinase inhibitors | MERCK & CO., INC. (US) | 2009-03-17 | — | — | US | claimed |