Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4488838 | 0.81 | CETP (0.31) | — | |
| SCHEMBL4497785 | 0.78 | TACR1 (0.40) | GPBAR1TACR1CCR2 | |
| SCHEMBL4496943 | 0.73 | AR (0.38) | GPBAR1TACR1 | |
| SCHEMBL4234307 | 0.71 | GPBAR1 (0.37) | GPBAR1TACR1CCR2 | |
| SCHEMBL5623662 | 0.71 | TACR1 (0.41) | GPBAR1TACR1CCR2 | |
| SCHEMBL4496663 | 0.69 | CETP (0.32) | — | |
| SCHEMBL5623804 | 0.69 | TACR1 (0.31) | GPBAR1TACR1 | |
| SCHEMBL5623686 | 0.68 | TACR1 (0.40) | GPBAR1TACR1CCR2 | |
| SCHEMBL5628380 | 0.68 | TACR1 (0.33) | GPBAR1TACR1CCR2 | |
| SCHEMBL5627070 | 0.68 | TACR1 (0.40) | GPBAR1TACR1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023729-A1 | Trisubstituted amine compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023729-A1 | Trisubstituted amine compound | CETP, MTTP, APOB | GPBAR1 270/4885TACR1 3300/4885CCR2 1966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.