Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547412 | 0.59 | ALDH1A1 (0.79) | ALDH1A1ALOX15TSHRHSD17B10MAPT | |
| SCHEMBL124209 | 0.59 | ALDH1A1 (0.79) | ALDH1A1ALOX15TSHRHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL30448295 | 0.57 | ALDH1A1 (0.73) | ALDH1A1ALOX15TSHRHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL31707017 | 0.57 | ALDH1A1 (0.73) | ALDH1A1ALOX15TSHRHSD17B10MAPT | |
| SCHEMBL65261 | 0.56 | ALDH1A1 (1.00) | ALDH1A1ALOX15TSHRHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL31597062 | 0.55 | ALDH1A1 (0.69) | ALDH1A1ALOX15TSHRHSD17B10MAPT | |
| Methyl Alcohol SCHEMBL6759181 | 0.55 | ALDH1A1 (0.69) | ALDH1A1ALOX15TSHRHSD17B10MAPT | |
| SCHEMBL13679719 | 0.54 | ALDH1A1 (0.58) | NOTUMALDH1A1ALOX15TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL379125 | 0.54 | ALDH1A1 (0.92) | ALDH1A1ALOX15TSHRHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL379126 | 0.54 | ALDH1A1 (0.92) | ALDH1A1ALOX15TSHRHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7632851-B2 | Benzo[1,2,5]oxadiazoles and benzol[1,2,5]thiadiazoles useful as histopathological staining agents, imaging agents and biomarkers | NOVARTIS AG (CH) | 2009-12-15 | — | — | US | disclosed |
| US-20060093551-A1 | Benzo[1,2,5]oxadiazoles and benzol[1,2,5]thiadiazoles useful as histopathological staining agents, imaging agents and biomarkers | NOVARTIS AG (CH) | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060093551-A1 | Benzo[1,2,5]oxadiazoles and benzol[1,2,5]thiadiazoles useful as histopathological staining agents, imaging agents and biomarkers | H1-3, MKI67, H1-5 | NOTUM 3595/4885PGR 1447/4885ALDH1A1 551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.