SCHEMBL449909

SCHEMBL449909

C=CCC(C=C)OC(=O)C=CC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 10/20 0.47
TSHR P16473 3/20 0.33
TP53 P04637 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
EGLN3 Q9H6Z9 1/20 0.33
GRIK1 P39086 2/20 0.31
GRIK2 Q13002 2/20 0.31
ABCC4 O15439 1/20 0.31
MAPT P10636 1/20 0.31
GABRR1 P24046 2/20 0.30
GABRR2 P28476 2/20 0.30
BLM P54132 2/20 0.30
GABRR3 A8MPY1 1/20 0.30
LMNA P02545 1/20 0.30
APEX1 P27695 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
CYP2C19 P33261 1/20 0.30
CPA1 P15085 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11520000 0.81 ALDH1A1 (0.31) HCAR2LMNA
SCHEMBL27397601 0.81 HCAR2 (0.50) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL28407507 0.80 TSHR (0.38) TSHRTP53GRIK1GRIK2
SCHEMBL5132469 0.78 GRIK1 (0.35) TSHRGRIK1GRIK2ABCC4MAPT
SCHEMBL8765468 0.78 HCAR2 (0.57) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL8765477 0.78 HCAR2 (0.57) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL11878376 0.77 HCAR2 (0.52) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL11879678 0.77 HCAR2 (0.52) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL11878382 0.77 HCAR2 (0.52) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL27517079 0.77 HCAR2 (0.40) HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 767 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12345137-B2 Swellable devices based on renewable raw materials and methods of using in wellbores BAKER HUGHES OILFIELD OPERATIONS LLC (US) 2025-07-01 US claimed
CN-119307207-A Negative electrode binder, negative electrode plate and electrochemical energy storage device 峻益天材(深圳)新能源有限公司 2025-01-14 CN claimed
CN-115418165-A Environment-friendly fouling organism protective coating (film) and preparation and application methods thereof 天津大学 2022-12-02 CN claimed
CN-110872368-B Formula of multi-double-bond polar compound modified semi-steel radial tire tread rubber 中国石油化工股份有限公司 2022-09-06 CN claimed
CN-110872404-B Multi-double-bond polar compound modified SSBR, preparation method thereof and semi-steel radial tire tread rubber formula 中国石油化工股份有限公司 2022-08-16 CN claimed
CN-110872403-B Multi-double-bond polar compound modified BR, preparation method thereof and tread rubber formula of semi-steel radial tire 中国石油化工股份有限公司 2022-07-08 CN claimed
CN-111378241-A Blue-light-proof resin composition and preparation method thereof 江苏可奥熙光学材料科技有限公司 2020-07-07 CN claimed
CN-110872368-A Formula of multi-double-bond polar compound modified semi-steel radial tire tread rubber 中国石油化工股份有限公司 2020-03-10 CN claimed
CN-110872403-A Multi-double-bond polar compound modified BR, preparation method thereof and tread rubber formula of semi-steel radial tire 中国石油化工股份有限公司 2020-03-10 CN claimed
CN-110872404-A Multi-double-bond polar compound modified SSBR, preparation method thereof and tread rubber formula of semi-steel radial tire 中国石油化工股份有限公司 2020-03-10 CN claimed
EP-1919960-B1 AMINO GROUP-TERMINAL VISCOSIFIERS, RESULTANT PRODUCTS AND USES THEREOF SIKA TECHNOLOGY AG (CH) 2009-05-27 EP claimed
CN-1969181-A Processable molecularly imprinted polymers UNIV JOHNS HOPKINS (US) 2007-05-23 CN claimed
CN-1591934-A Positive electrode with polymer film and lithium-sulfur cell using the positive electrode SAMSUNG SDI CO LTD (KR) 2005-03-09 CN claimed
CN-1189762-C Opthalmic lens made of organic glass, comprising an anti-shock primer coat ESSILOR INTERNAT GENERAL OPTIC (FR) 2005-02-16 CN claimed
CN-1300371-A Opthalmic lens made of organic glass, comprising an anti-shock primer coat ESSILOR INTERNAT GENERAL OPTIC (FR) 2001-06-20 CN claimed
CN-1031820-C Weak acidic cation exchanging resin producing process UNIV NANKAI (CN) 1996-05-22 CN claimed
US-5350822-A Divinyl-spirobi/m-dioxane/ INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1994-09-27 US claimed
CN-1088486-A Weak acidic cation exchanging resin producing process UNIV NANKAI (CN) 1994-06-29 CN claimed
EP-0008114-B1 PROCESS FOR THE PREPARATION OF GLYCIDYL ESTERS OF MALEIC ACID BAYER AG (DE) 1983-01-19 EP claimed
US-4048130-A COPOLYMERIZATION, UNSATURATED ACIDS LONZA LTD. (CH) 1977-09-13 US claimed