Pentetic Acid

Pentetic Acid

SCHEMBL449956

O=C([O-])CN(CCN(CC(=O)[O-])CC(=O)[O-])CCN(CC(=O)[O-])CC(=O)[O-].O=C([O-])CN(CCN(CC(=O)[O-])CC(=O)[O-])CCN(CC(=O)[O-])CC(=O)[O-].O=C([O-])CN(CCN(CC(=O)[O-])CC(=O)[O-])CCN(CC(=O)[O-])CC(=O)[O-].[Gd+3].[Gd+3].[Gd+3].[Gd+3].[Gd+3]

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.73
ALOX15 P16050 2/20 0.73
MAPT P10636 1/20 0.73
SMN1; SMN2 Q16637 1/20 0.73
TDP1 Q9NUW8 2/20 0.52
BLM P54132 2/20 0.52
PMP22 Q01453 2/20 0.52
LMNA P02545 1/20 0.52
CHRM2 P08172 1/20 0.52
ADRA2A P08913 1/20 0.52
TSHR P16473 1/20 0.52
DRD1 P21728 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A4 P31645 1/20 0.52
CYP2C19 P33261 1/20 0.52
ADRA1A P35348 1/20 0.52
DRD3 P35462 1/20 0.52
SLC6A3 Q01959 1/20 0.52
HRH3 Q9Y5N1 1/20 0.52
EYA2 O00167 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pentetic Acid SCHEMBL1812238 0.97 KDM4E (0.70) KDM4EALOX15MAPTSMN1; SMN2TDP1
Pentetic Acid SCHEMBL8372011 0.97 KDM4E (0.77) KDM4EALOX15MAPTSMN1; SMN2TDP1
Edetic Acid SCHEMBL5056266 0.97 KDM4E (0.68) KDM4EALOX15MAPTSMN1; SMN2TDP1
Pentetic Acid SCHEMBL2800920 0.94 KDM4E (0.73) KDM4EALOX15MAPTSMN1; SMN2TDP1
Pentetic Acid SCHEMBL1478010 0.94 KDM4E (0.73) KDM4EALOX15MAPTSMN1; SMN2TDP1
Pentetic Acid SCHEMBL5193980 0.94 KDM4E (0.73) KDM4EALOX15MAPTSMN1; SMN2TDP1
Edetic Acid SCHEMBL6670902 0.94 KDM4E (0.65) KDM4EALOX15MAPTSMN1; SMN2TDP1
Pentetic Acid SCHEMBL5352521 0.94 KDM4E (0.73) KDM4EALOX15MAPTSMN1; SMN2TDP1
Pentetic Acid SCHEMBL2274186 0.94 KDM4E (0.73) KDM4EALOX15MAPTSMN1; SMN2TDP1
Pentetic Acid SCHEMBL1477452 0.94 KDM4E (0.73) KDM4EALOX15MAPTSMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11676750-B2 Magnetic levitation PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-06-13 US claimed
CN-115590824-A Polyvinyl alcohol embolism microsphere with developer and preparation method and application thereof 浙江大学(CN) 2023-01-13 CN claimed
CN-108289970-B Formulations comprising a combination of MRI contrast agents 通用电气医疗集团股份有限公司 2022-04-08 CN claimed
US-20220013268-A1 MAGNETIC LEVITATION PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2022-01-13 US claimed
CN-113728232-A IL-4R as a biomarker in cancer 梅迪塞纳医疗股份有限公司 2021-11-30 CN claimed
CN-107899025-B Glucan-gadolinium MRI nano developer and preparation method thereof 上海交通大学 2020-12-11 CN claimed
CN-111405911-A I L-4 fusion preparation for treating Central Nervous System (CNS) tumors 梅迪塞纳医疗股份有限公司 2020-07-10 CN claimed
US-10702612-B2 Conjugated polymer-based nanoprobe and preparation method and application thereof SHANGHAI JIAO TONG UNIVERSITY (CN) 2020-07-07 US claimed
US-20120065384-A1 FLUORESCENT MRI PROBE THE UNIVERSITY OF TOKYO (JP) 2012-03-15 US claimed
JP-4790215-B2 2011-10-12 JP claimed
EP-1107985-A1 BASIC PEPTIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME NST Neurosurvival Technologies Ltd. (IL) 2001-06-20 EP claimed
WO-2001018031-A2 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME NST NEUROSURVIVAL TECHNOLOGIES LTD. (IL) 2001-03-15 WO claimed
WO-2000011026-A1 BASIC PEPTIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME NST NEUROSURVIVAL TECHNOLOGIES LTD. (IL) 2000-03-02 WO claimed
EP-0467031-B1 Medical-grade lipid-coated microbubbles, paramagnetic labelling thereof and their therapeutic use CAVITATION CONTROL TECHNOLOGY (US) 1997-07-30 EP claimed
US-5514379-A Hydrogel compositions and methods of use THE GENERAL HOSPITAL CORPORATION (US) 1996-05-07 US claimed
WO-1995033494-A1 EMULSIONS OF PARAMAGNETIC CONTRAST AGENTS FOR MAGNETIC RESONANCE IMAGING (MRI), CONTAINING AN ORGANIC CHELATOR HAVING AN UNSATURATED ALIPHATIC GROUP HEMAGEN/PFC (US) 1995-12-14 WO claimed
US-5362475-A Salt of gadolinium diethylenetriaminepentaacetic acid (gadofosveset salt) SCHERING AKTIENGESELLSCHAFT (DE) 1994-11-08 US claimed
WO-1994003155-A1 HYDROGEL COMPOSITIONS AND METHODS OF USE THE GENERAL HOSPITAL CORPORATION (US) 1994-02-17 WO claimed
EP-0467031-A2 Medical-grade lipid-coated microbubbles, paramagnetic labelling thereof and their therapeutic use CAVITATION-CONTROL TECHNOLOGY, INC. (US) 1992-01-22 EP claimed
US-4957939-A AMINOCARBOXYLIC ACIDS, MEDICAL IMAGING SCHERING AKTIENGESELLSCHAFT (DE) 1990-09-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10702612-B2 Conjugated polymer-based nanoprobe and preparation method and application thereof CD69, MYD88, VEGFA KDM4E 4770/4885ALOX15 2473/4885MAPT 530/4885
US-20120065384-A1 FLUORESCENT MRI PROBE GLRA1, GLRA3, GDI1 KDM4E 4398/4885ALOX15 4566/4885MAPT 3584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.