Sugi Predict
/ Targets
/ GDI1
Top predicted compounds (top 20 by supporting neighbours, then confidence)
| Compound | Confidence | Supporting neighbours |
|---|
Clinical trials — most relevant to GDI1 by text similarity (a relevance ranking, not an exhaustive list)
| Trial | Phase | Status |
|---|
| A Study of Enzyme Replacement Therapy (VPRIV) in People With Type 1 Gaucher Disease Who Were Previously Treated With Substrate Reduction Therapy |
PHASE4 | COMPLETED |
| Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in GBA-PD |
PHASE2 | ACTIVE_NOT_RECRUITING |
| Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47) |
PHASE1/PHASE2 | NOT_YET_RECRUITING |
| Pembrolizumab (MK-3475) in MM Patients With Residual Disease |
PHASE2 | COMPLETED |
| Simvastatin + Cetuximab/Irinotecan in K-ras Mutant Colorectal Cancer (CRC) |
PHASE2 | COMPLETED |
| A Trial to Evaluate Safety and Efficacy of a Product Named VGN-R08b in Parkinson's Disease Patients With GBA1 Mutations |
PHASE1/PHASE2 | NOT_YET_RECRUITING |
| Phase 1/2 Study of CAN103 in Subjects With Gaucher Disease |
PHASE1/PHASE2 | UNKNOWN |
| Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GT-02287 in Parkinson's Disease |
PHASE1 | RECRUITING |
| GNAO1 Natural History Study |
nan | UNKNOWN |
| Taxonomy of Neurodegenerative Diseases : Observational Study in Alzheimer's Disease and Parkinson's Disease |
nan | COMPLETED |
| ADRB3, ROCK2 and GEF Levels in Overactive Bladder Patients |
nan | COMPLETED |
| PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort |
nan | RECRUITING |
| Biomarker Analysis for GBA Associated Parkinson's Disease |
nan | UNKNOWN |
| Genetic Studies of Lysosomal Storage Disorders |
nan | ENROLLING_BY_INVITATION |
| NGLY1 Natural History |
nan | COMPLETED |
| Genetic Investigations in Children With Developmental and Epileptic Encephalopathies in Ho Chi Minh City, Vietnam |
nan | UNKNOWN |
| Exploration of Immunity in Gaucher Disease |
nan | COMPLETED |
| A Prospective Study to Evaluate Clinical Outcomes in Anti-LGI1 Encephalitis |
nan | RECRUITING |
| Study on the Carcinogenesis of Gα12 in Oral Cancer, and the Treatment of Oral Cancer Using Ga12 Inhibitor. |
nan | UNKNOWN |
| Positron Emission Tomography (PET) Imaging in People With Gaucher Mutations |
nan | COMPLETED |
| Biomarkers Related to Bone in Pediatric Gaucher Disease |
nan | UNKNOWN |
| Transcranial Magnetic Stimulation (TMS) Studies of Dystonia |
nan | COMPLETED |
| PD Frontline (Part of RAPSODI GD) Remote Assessment of People With Parkinson's |
nan | RECRUITING |
| Extracellular Vesicles as Potential Biomarkers and Therapeutic Target in Gaucher Disease |
nan | RECRUITING |
| Non Motor Symptoms in Glucocerebrosidase-related Parkinson's Disease |
nan | ENROLLING_BY_INVITATION |
| Immune Biomarkers Related to Bone Pathology in Patients With Type 1 Gaucher Disease |
nan | UNKNOWN |
| Study of People With Generalized Arterial Calcification of Infancy (GACI) or Autosomal Recessive Hypophosphatemic Rickets Type 2 (ARHR2) |
nan | COMPLETED |
| AV133 Longitudinal Imaging Study in Patients With Early and Prdromal Parkinson's Disease |
nan | RECRUITING |
| Long-read Genome Sequencing for the Molecular Diagnosis of Dystonia |
nan | RECRUITING |
| Registry Gangliosidoses |
nan | UNKNOWN |
Related proteins — ESM-2 sequence neighbours (a GDI1 binder may also engage these)