Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | LYN | P07948 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | MARK3 | P27448 | 1/20 | 0.42 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15968669 | 0.78 | AURKA (0.63) | AURKANPC1MAPTMAPK1RAB9A | |
| SCHEMBL911 | 0.78 | AURKA (0.63) | AURKANPC1MAPTMAPK1RAB9A | |
| SCHEMBL27417170 | 0.77 | MAPT (0.63) | AURKANPC1MAPTMAPK1RAB9A | |
| SCHEMBL1120968 | 0.77 | AURKA (0.42) | AURKANPC1MAPTMAPK1RAB9A | |
| SCHEMBL27714382 | 0.77 | SCN9A (0.59) | NPC1RAB9ACDK2MEN1KMT2A | |
| SCHEMBL3786298 | 0.77 | HPGD (0.54) | NPC1MAPTRAB9ACDK1CDK2 | |
| SCHEMBL1120994 | 0.77 | PIK3CG (0.51) | AURKANPC1MAPTMAPK1RAB9A | |
| SCHEMBL4583809 | 0.77 | RAD52 (0.56) | AURKANPC1MAPTMAPK1RAB9A | |
| SCHEMBL4498501 | 0.77 | AURKA (0.63) | AURKANPC1MAPTRAB9ACDK2 | |
| SCHEMBL29348777 | 0.77 | MEN1 (0.55) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2039687-B1 | THERAPEUTIC OR PROPHYLACTIC AGENT FOR MULTIPLE SCLEROSIS | TORAY INDUSTRIES (JP) | 2012-05-02 | — | — | EP | disclosed |