SCHEMBL911

SCHEMBL911

c1ccc(Nc2ncccn2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AURKA O14965 4/20 0.63
MAPK1 P28482 3/20 0.63
MAPT P10636 3/20 0.63
CDK1 P06493 3/20 0.63
PRKCD Q05655 2/20 0.63
PDPK1 O15530 2/20 0.63
LYN P07948 2/20 0.63
FGFR1 P11362 2/20 0.63
FGFR3 P22607 2/20 0.63
RPS6KB1 P23443 2/20 0.63
CDK2 P24941 2/20 0.63
MARK3 P27448 2/20 0.63
BLK P51451 2/20 0.63
RPS6KA3 P51812 2/20 0.63
ERBB4 Q15303 2/20 0.63
MARK2 Q7KZI7 2/20 0.63
PLK3 Q9H4B4 2/20 0.63
CHEK1 O14757 1/20 0.63
IKBKB O14920 1/20 0.63
NPC1 O15118 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15968669 1.00 AURKA (0.63) AURKAMAPK1MAPTCDK1PRKCD
Hydrochloric Acid SCHEMBL6820971 0.97 MAPK1 (0.61) AURKAMAPK1MAPTCDK1PRKCD
Ammonia Solution, Strong SCHEMBL28789700 0.97 MAPT (0.61) AURKAMAPK1MAPTCDK1PRKCD
SCHEMBL6370265 0.97 AURKA (0.61) AURKAMAPK1MAPTCDK1PRKCD
Pyrimidine SCHEMBL27837500 0.89 MAPT (0.53) AURKAMAPK1MAPTCDK1PRKCD
SCHEMBL29484614 0.87 MAPT (0.52) AURKAMAPK1MAPTCDK1PRKCD
SCHEMBL27835195 0.86 PRKCD (0.50) AURKAMAPK1MAPTCDK1PRKCD
Pyrimethanil SCHEMBL1467035 0.82 SMN1; SMN2 (0.61) AURKAMAPK1MAPTCDK1PRKCD
SCHEMBL5823445 0.82 RAD52 (0.48) AURKAMAPK1MAPTCDK1PRKCD
SCHEMBL27753867 0.81 AURKA (0.46) AURKAMAPK1MAPTCDK1PRKCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 14008 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260060936-A1 INDOLIUM-BASED STABILIZERS OF HYDROPHOBIC DRUGS TECHNION RES & DEV FOUNDATION (IL) 2026-03-05 US claimed
EP-4649827-A2 FUNGICIDAL MIXTURES ADAMA MAKHTESHIM LTD. (IL) 2025-11-19 EP claimed
EP-4637347-A1 OIL FLOWABLE APYRASE INHIBITOR FORMULATION Texas Crop Science, Inc. (US) 2025-10-29 EP claimed
EP-4618758-A1 MIXTURES OF SUCCINATE DEHYDROGENASE INHIBITORS AND PICOLINAMIDES FMC Corporation (US) 2025-09-24 EP claimed
EP-4608136-A1 WATER DISPERSIBLE GRANULE ACYLHYDRAZONE APYRASE INHIBITOR FORMULATION Texas Crop Science, Inc. (US) 2025-09-03 EP claimed
EP-4604724-A1 SUSPENSION CONCENTRATE ACYLHYDRAZONE APYRASE INHIBITOR FORMULATION Texas Crop Science, Inc. (US) 2025-08-27 EP claimed
CN-120166922-A Apyrase inhibitors 德州作物科学股份有限公司 2025-06-17 CN claimed
US-20250185655-A1 PHEROMONE COMPOSITIONS, METHODS OF MAKING, AND THEIR USES PHERONYM INC. (US) 2025-06-12 US claimed
CN-119912432-A Method for synthesizing carbazole derivative by using water as reaction solvent through multicomponent one-pot method 天津力生制药股份有限公司 2025-05-02 CN claimed
US-20250098677-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2025-03-27 US claimed
WO-1995009847-A1 PYRIMIDINEAMINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF CIBA-GEIGY AG (CH) 1995-04-13 WO claimed
US-5403844-A Synergistic triazole fungicides and pyrimidinamine fungicide mixtures CIBA-GEIGY CORPORATION (US) 1995-04-04 US claimed
CN-1099220-A Microbicide CIBA GEIGY AG (CH) 1995-03-01 CN claimed
EP-0630569-A2 Microbicides CIBA-GEIGY AG (CH) 1994-12-28 EP claimed
US-5373013-A Microbicides CIBA-GEIGY CORPORATION (US) 1994-12-13 US claimed
EP-0627164-A1 Microbicidal compositions comprising prochloraz and cyprodinil CIBA-GEIGY AG (CH) 1994-12-07 EP claimed
EP-0556157-A1 Fungicidal mixtures based on triazole fungicides and 4,6-dimethyl-N-phenyl-2-pyrimidinamine CIBA-GEIGY AG (CH) 1993-08-18 EP claimed
EP-0347866-B1 ANILINOPYRIMIDINE DERIVATIVES IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) 1993-04-07 EP claimed
EP-0347866-A2 Anilinopyrimidine derivatives IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) 1989-12-27 EP claimed
EP-0024017-A2 N-pyrimidinylmethyl-haloacetanilides, process for their preparation and their use as herbicides; intermediates and their preparation BAYER AG (DE) 1981-02-18 EP claimed