⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149819 | 0.82 | — | — | |
| SCHEMBL471953 | 0.77 | — | — | |
| SCHEMBL6387994 | 0.74 | — | — | |
| SCHEMBL428796 | 0.72 | LMNA (0.38) | — | |
| SCHEMBL105133 | 0.71 | — | — | |
| SCHEMBL491157 | 0.69 | — | — | |
| SCHEMBL3511006 | 0.69 | — | — | |
| SCHEMBL1828351 | 0.69 | — | — | |
| SCHEMBL735965 | 0.69 | — | — | |
| SCHEMBL8198407 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 382 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11325886-B2 | Amide compounds, pharmaceutical compositions thereof, and methods of using the same | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2022-05-10 | — | — | US | claimed |
| CN-114437554-A | Industrial oil sludge and preparation method thereof | 上海藤轲汽车技术有限公司 | 2022-05-06 | — | — | CN | claimed |
| US-20210284599-A1 | AMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-09-16 | — | — | US | claimed |
| CN-109732038-B | Die-casting release agent and preparation method thereof | 宁波辉宏新材料有限公司 | 2021-04-06 | — | — | CN | claimed |
| EP-3497077-A1 | AMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | Oregon Health & Science University (US) | 2019-06-19 | — | — | EP | claimed |
| CN-109843849-A | Amide compounds, pharmaceutical compositions thereof, and methods of use thereof | 俄勒冈健康科学大学 | 2019-06-04 | — | — | CN | claimed |
| WO-2018032012-A1 | AMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2018-02-15 | — | — | WO | claimed |
| CN-104173321-B | The method for preparing pharmaceutical composition being administered by external use plaster, with anti-inflammatory analgesic activity, and the composition obtained with this | 阿尔特根有限公司 | 2017-10-31 | — | — | CN | claimed |
| CN-103435569-A | Novel salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents | FERROKIN BIOSCIENCES INC | 2013-12-11 | — | — | CN | claimed |
| CN-102149700-A | Novel salts and polymorphs of desazadesferrothiocin polyether analogues as metal chelation agents | FERROKIN BIOSCIENCES INC | 2011-08-10 | — | — | CN | claimed |
| US-7053031-B2 | Cleaning agents for the outer surfaces of means of transport | CLARIANT GMBH (DE) | 2006-05-30 | — | — | US | claimed |
| US-20050203094-A1 | 2-[5-(5-carbamimidoyl-1h-heteroaryl)]-6-hydroxybiphenyl-3-yl derivatives as factor viia inhibitors | AXYS PHARMACEUTICALS, INC. | 2005-09-15 | — | — | US | claimed |
| US-20050107408-A1 | Hydroxyalkyl substituted pyrido-7-pyrimidin-7-ones | ROCHE PALO ALTO LLC | 2005-05-19 | — | — | US | claimed |
| US-20050003558-A1 | Biological sample component purification and differential display | CHIRON CORPORATION (US) | 2005-01-06 | — | — | US | claimed |
| EP-1474400-A1 | 2-[5-(5-CARBAMIMIDOYL-1H-HETEROARYL)] -6-HYDROXYBIPHENYL-3-YL DERIVATIVES AS FACTOR VIIA INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2004-11-10 | — | — | EP | claimed |
| US-6783929-B1 | COMPRISES POLYAMIDE LIGANDS FOR ENHANCED EFFICIENCY OF PROTEOMICS | CHIRON CORPORATION | 2004-08-31 | — | — | US | claimed |
| WO-2003068756-A1 | 2-[5-(5-CARBAMIMIDOYL-1H-HETEROARYL)]-6-HYDROXYBIPHENYL-3-YL DERIVATIVES AS FACTOR VIIA INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2003-08-21 | — | — | WO | claimed |
| EP-1155327-A1 | BIOLOGICAL SAMPLE COMPONENT PURIFICATION AND DIFFERENTIAL DISPLAY | CHIRON CORPORATION (US) | 2001-11-21 | — | — | EP | claimed |
| WO-2001033230-A2 | BIOLOGICAL SAMPLE COMPONENT PURIFICATION AND DIFFERENTIAL DISPLAY | CHIRON CORPORATION (US) | 2001-05-10 | — | — | WO | claimed |
| EP-0284174-B1 | THERAPEUTIC PREPARATIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-29 | — | — | EP | claimed |