Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 14/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 13/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.42 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.42 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885045 | 0.91 | KCNA5 (0.42) | CYP3A4CYP2C9CYP1A2CYP2C19MEN1 | |
| SCHEMBL2887759 | 0.83 | KCNA5 (0.44) | CYP3A4CYP2C9CYP1A2CYP2C19MEN1 | |
| SCHEMBL2882170 | 0.82 | CYP3A4 (0.45) | CYP3A4CYP2C9CYP1A2CYP2C19MEN1 | |
| SCHEMBL4284475 | 0.80 | KCNA5 (0.42) | CYP3A4CYP2C9CYP1A2CYP2C19MEN1 | |
| SCHEMBL4109997 | 0.76 | KCNA5 (0.42) | CYP3A4CYP2C9KCNA5KCNH2KCNA3 | |
| SCHEMBL4284478 | 0.71 | KCNA5 (0.41) | CYP3A4CYP2C9KCNA5KCNH2KCNA3 | |
| SCHEMBL2884875 | 0.69 | KCNA5 (0.53) | CYP3A4CYP2C9CYP1A2CYP2C19MEN1 | |
| SCHEMBL3991934 | 0.69 | KCNA5 (0.49) | CYP3A4CYP2C9CYP1A2CYP2C19MEN1 | |
| SCHEMBL2886341 | 0.66 | KCNA5 (0.64) | CYP3A4CYP2C9KCNA5KCNH2KCNA3 | |
| SCHEMBL2884973 | 0.65 | KCNA5 (0.62) | CYP3A4CYP2C9KCNA5KCNH2KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069342-A1 | KV1.5 POTASSIUM CHANNEL INHIBITORS | WYETH (US) | 2009-03-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069342-A1 | KV1.5 POTASSIUM CHANNEL INHIBITORS | KCNJ2, KCNK5, KCNH2 | CYP3A4 1139/4885CYP2C9 1340/4885CYP1A2 961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.