SCHEMBL450261

SCHEMBL450261

Oc1cccc(Oc2ccccc2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.62
NR1H2 P55055 1/20 0.62
BAX Q07812 1/20 0.62
TSHR P16473 1/20 0.57
MAOB P27338 1/20 0.56
AKR1C3 P42330 1/20 0.55
CYP3A4 P08684 2/20 0.50
ALDH1A1 P00352 2/20 0.50
CA12 O43570 1/20 0.50
CA2 P00918 1/20 0.50
LMNA P02545 1/20 0.50
CA5A P35218 1/20 0.50
CA9 Q16790 1/20 0.50
HSD17B10 Q99714 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
HDAC8 Q9BY41 1/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
CASP3 P42574 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10337742 0.98 LTA4H (0.60) LTA4HNR1H2BAXTSHRMAOB
SCHEMBL9385056 0.98 LTA4H (0.67) LTA4HNR1H2BAXTSHRMAOB
SCHEMBL11817541 0.98 LTA4H (0.60) LTA4HNR1H2BAXTSHRMAOB
SCHEMBL1174127 0.98 LTA4H (0.60) LTA4HNR1H2BAXTSHRMAOB
Nitrogen SCHEMBL10337741 0.96 LTA4H (0.58) LTA4HNR1H2BAXTSHRMAOB
Diphenylether SCHEMBL1252647 0.93 LTA4H (0.65) LTA4HNR1H2BAXTSHRMAOB
SCHEMBL8076305 0.93 LTA4H (0.58) LTA4HNR1H2BAXTSHRMAOB
SCHEMBL29458645 0.93 LTA4H (0.58) LTA4HNR1H2BAXTSHRMAOB
SCHEMBL5027612 0.93 LTA4H (0.58) LTA4HNR1H2BAXTSHRMAOB
SCHEMBL813557 0.93 CYP3A4 (0.58) LTA4HNR1H2BAXTSHRAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1695 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115838447-B Catalyst component for olefin polymerization, preparation method and application thereof, catalyst and application thereof 中国石油化工股份有限公司 2023-09-08 CN claimed
CN-116675861-A Preparation method of modified polyethersulfone/polyetherimide polymer alloy 深圳先进技术研究院 2023-09-01 CN claimed
CN-114436925-B M-diphenol ether compound, preparation method and application thereof 河北大学 2023-08-15 CN claimed
CN-115838447-A Catalyst component for olefin polymerization, preparation method and application thereof, catalyst and application thereof 中国石油化工股份有限公司 2023-03-24 CN claimed
CN-112961340-A Quaternary copolymerized polyaryletherketone, and preparation method and application thereof 吉林大学 2021-06-15 CN claimed
CN-104987509-A Polymer containing ester group and amino group, preparation method, polymer containing carboxyl group and amino group, preparation method, and proton exchange membrane UNIV CHANGCHUN TECHNOLOGY 2015-10-21 CN claimed
US-9057127-B2 Plated resin molded articles DAICEL POLYMER LTD. (JP) 2015-06-16 US claimed
CN-104693327-A Bi-metal semi-metallocene catalyst and preparation method and application thereof UNIV BEIJING CHEMICAL 2015-06-10 CN claimed
US-20140135297-A1 AQUEOUS VOLATILE ORGANIC COMPOUND FREE DISINFECTANT AND/OR CLEANING COMPOSITION AND METHOD OF PREPARATION ISP INVESTMENTS INC. (US) 2014-05-15 US claimed
CN-102304119-B Amino-containing circular aryl ether ketone monomer, and synthesis method and application thereof UNIV JILIN 2013-10-16 CN claimed
US-5464569-A In situ formation of alkali metal oxalates in polyphenylene ether basestock MONSANTO COMPANY (US) 1995-11-07 US claimed
EP-0606183-A1 Process for the preparation of a P-fuchsone and its use in the preparation of an aromatic p-dihydroxylated compound RHONE-POULENC CHIMIE (FR) 1994-07-13 EP claimed
US-5219477-A Containing organometallic salts and inorganic metal borates; fromo reactinmetal hydroxide with phenols or aromatic carboxylic acid THE DOW CHEMICAL COMPANY (US) 1993-06-15 US claimed
US-4952718-A Reduction of cyanohydrins ETHYL CORPORATION (US) 1990-08-28 US claimed
EP-0003295-B1 PHENOXY-PHENOXY-ALKYLCARBOXYLIC ACID DERIVATIVES WITH HERBICIDAL ACTIVITY, THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR USE CIBA-GEIGY AG (CH) 1981-11-25 EP claimed
US-4268693-A 3-Hydroxydiphenyl ethers CIBA-GEIGY CORPORATION (US) 1981-05-19 US claimed
EP-0003297-B1 PHENOXY-ALKYL-OXAZOLINES, THEIR PREPARATION, HERBICIDE COMPOSITIONS CONTAINING THEM, AND THEIR APPLICATION CIBA-GEIGY AG (CH) 1981-05-13 EP claimed
EP-0003295-A1 Phenoxy-phenoxy-alkylcarboxylic acid derivatives with herbicidal activity, their preparation, compositions containing them and their use CIBA-GEIGY AG (CH) 1979-08-08 EP claimed
EP-0003297-A1 Phenoxy-alkyl-oxazolines, their preparation, herbicide compositions containing them, and their application CIBA-GEIGY AG (CH) 1979-08-08 EP claimed
US-4107439-A Process for preparing arylalkanoic acid derivatives THE UPJOHN COMPANY (US) 1978-08-15 US claimed