⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1374641 | 0.82 | — | — | |
| SCHEMBL14427919 | 0.80 | ALDH1A1 (0.38) | — | |
| SCHEMBL3214514 | 0.73 | — | — | |
| SCHEMBL9418654 | 0.71 | — | — | |
| SCHEMBL9418657 | 0.71 | — | — | |
| Ammonia Solution, Strong SCHEMBL9418650 | 0.71 | — | — | |
| SCHEMBL7194986 | 0.71 | — | — | |
| SCHEMBL29276731 | 0.66 | ESR2 (0.39) | — | |
| SCHEMBL9368368 | 0.65 | — | — | |
| SCHEMBL691808 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210115087-A1 | CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS | UNIV ROCHESTER (US) | 2021-04-22 | — | — | US | claimed |
| US-20190241615-A1 | CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS | UNIVERSITY OF ROCHESTER | 2019-08-08 | — | — | US | claimed |
| EP-3475294-A1 | CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS | The University of Rochester (US) | 2019-05-01 | — | — | EP | claimed |
| WO-2017223207-A1 | CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS | UNIVERSITY OF ROCHESTER (US) | 2017-12-28 | — | — | WO | claimed |
| EP-0440251-B1 | Process for preparing optically active cyclopentenones | SUMITOMO CHEMICAL CO (JP) | 1995-09-06 | — | — | EP | claimed |
| US-5191109-A | Process for preparing optically active cyclopentenones | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-03-02 | — | — | US | claimed |
| EP-0440251-A2 | Process for preparing optically active cyclopentenones | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-08-07 | — | — | EP | claimed |
| EP-0213313-A2 | Precursors and synthesis of methyl-9-oxo-11 alpha, 16-dihydroxy-16-vinyl-5-cis-13-trans prostadienoates | AMERICAN CYANAMID COMPANY (US) | 1987-03-11 | — | — | EP | claimed |
| US-4304934-A | Synthesis of amino hydroxy cyclopentenones | POLAROID CORPORATION (US) | 1981-12-08 | — | — | US | claimed |
| JP-4211398-A | — | — | None | — | — | JP | disclosed |
| EP-4619401-A1 | AHR AGONISTS | Eli Lilly and Company (US) | 2025-09-24 | — | — | EP | disclosed |
| US-12264169-B2 | Heteroaryl inhibitors of PDE4 | Tetra Discovery Partners (US) | 2025-04-01 | — | — | US | disclosed |
| WO-2024107555-A1 | AHR AGONISTS | ELI LILLY AND COMPANY (US) | 2024-05-23 | — | — | WO | disclosed |
| US-20230348501-A1 | HETEROARYL INHIBITORS OF PDE4 | Tetra Discovery Partners, LLC | 2023-11-02 | — | — | US | disclosed |
| US-4178456-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1979-12-11 | — | — | US | disclosed |
| US-4172839-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1979-10-30 | — | — | US | disclosed |
| US-4170597-A | 1-Hydroxymethyl-1-oxo-prostane derivatives of the E2 series | AMERICAN CYANAMID COMPANY (US) | 1979-10-09 | — | — | US | disclosed |
| EP-0002590-A1 | Novel prostaglandin compounds, processes for the preparation thereof and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-06-27 | — | — | EP | disclosed |
| US-4131737-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1978-12-26 | — | — | US | disclosed |
| US-4109662-A | SMOKING | FRITZSCHE DODGE & OLCOTT INC. (US) | 1978-08-29 | — | — | US | disclosed |