Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 3/20 | 0.32 |
| ▸ | SI | P14410 | 3/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.32 |
| ▸ | GALK1 | P51570 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13614127 | 0.88 | HTT (0.42) | HTTKMT2ACYP1A2ALDH1A1CYP2C19 | |
| SCHEMBL4621206 | 0.86 | HTT (0.38) | HTTKMT2ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8407690 | 0.80 | HTT (0.41) | HTTHSD17B10 | |
| SCHEMBL4505232 | 0.79 | ALDH1A1 (0.39) | HTTCYP1A2ALDH1A1CYP2C19CYP3A4 | |
| SCHEMBL4621204 | 0.78 | HTT (0.44) | HTTKMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL4505005 | 0.78 | HTT (0.41) | HTTKMT2AALDH1A1GAAKDM4E | |
| SCHEMBL8658222 | 0.78 | HTT (0.39) | HTTHSD17B10 | |
| SCHEMBL4125338 | 0.78 | HTT (0.39) | HTTCYP1A2CYP2D6ALDH1A1CYP2C19 | |
| SCHEMBL8660426 | 0.77 | ALDH1A1 (0.41) | HTTKMT2AMAPTCYP1A2CYP2D6 | |
| SCHEMBL4511160 | 0.77 | ALDH1A1 (0.44) | HTTKMT2AMAPTCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042957-A1 | Substituted Oxyarenes | BAYER CROPSCIENCE AG (DE) | 2009-02-12 | — | — | US | disclosed |
| EP-1831145-A1 | SUBSTITUTED OXYARENES | Bayer CropScience Aktiengesellschaft (DE) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006069685-A1 | SUBSTITUTED OXYARENES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-07-06 | — | — | WO | disclosed |
| EP-1638962-A2 | SUBSTITUTED OXYARENES UND DEREN VERWENDUNG ZUR BEKÄMPFUNG VON SCHÄDLINGEN | Bayer CropScience AG (DE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004099197-A2 | SUBSTITUTED OXYARENES, AND USE THEREOF FOR CONTROLLING PESTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042957-A1 | Substituted Oxyarenes | CYP1A1, OXER1, CYP1A2 | HTT 3097/4885KMT2A 1738/4885MAPT 3759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.