Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND2 | P30279 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3606589 | 0.82 | HSD17B10 (0.44) | HSD17B10CYP1A2MAOAPTPRCPTPN13 | |
| SCHEMBL3606587 | 0.81 | HSD17B10 (0.43) | HSD17B10CYP1A2MAOAPTPRCPTPN13 | |
| SCHEMBL4503147 | 0.81 | L3MBTL1 (0.53) | HSD17B10CYP1A2MAOAALDH1A1SMN1; SMN2 | |
| SCHEMBL4516142 | 0.74 | SMN1; SMN2 (0.57) | ALDH1A1SMN1; SMN2KDM4EHPGDL3MBTL1 | |
| SCHEMBL3611242 | 0.74 | HSD17B10 (0.47) | HSD17B10CYP1A2MAOAPTPRCPTPN13 | |
| SCHEMBL3611245 | 0.74 | HSD17B10 (0.51) | HSD17B10CYP1A2MAOAPTPRCPTPN13 | |
| SCHEMBL10495494 | 0.73 | MAPT (0.35) | HSD17B10CYP1A2MAOAPTPRCPTPN13 | |
| SCHEMBL6541790 | 0.72 | CYP1A2 (0.43) | HSD17B10CYP1A2PTPRCPTPN13CDK4 | |
| SCHEMBL4500674 | 0.71 | KDM4E (0.58) | HSD17B10CYP1A2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8421703 | 0.69 | NPC1 (0.57) | ALDH1A1SMN1; SMN2KDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233960-A1 | Kinase Inhibitors | DEVGEN NV (BE) | 2009-09-17 | — | — | US | disclosed |
| EP-1934181-A2 | KINASE INHIBITORS | Devgen NV (BE) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007042321-A2 | KINASE INHIBITORS | DEVGEN N.V. (BE) | 2007-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233960-A1 | Kinase Inhibitors | ROCK1, MAP3K1, MAP3K11 | HSD17B10 2684/4885CYP1A2 1743/4885MAOA 2917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.