SCHEMBL450319

SCHEMBL450319

COc1cnco1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15966006 0.73 LMNA (0.32)
SCHEMBL17074390 0.69 NAMPT (0.32)
SCHEMBL2171046 0.66
SCHEMBL47206 0.65
SCHEMBL3137449 0.64
SCHEMBL472471 0.63 LMNA (0.63)
SCHEMBL8005615 0.62 LMNA (0.61)
SCHEMBL27246668 0.61
SCHEMBL683349 0.58
SCHEMBL18483391 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240383856-A1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2024-11-21 US claimed
US-7297168-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2007-11-20 US claimed
US-20050198745-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-09-15 US claimed
CN-115466220-A Bisazo five-membered azole ring monomer with three-order nonlinear optical performance, polymer thereof and preparation method thereof 盐城工学院 2022-12-13 CN disclosed
WO-2021018195-A1 NOVEL TRICYCLIC COMPOUNDS AS BCR-ABL INHIBITORS ASCENTAGE PHARMA (SUZHOU) CO., LTD. (CN) 2021-02-04 WO disclosed
US-9504728-B2 Dosage form NEUROVIVE PHARMACEUTICAL AB (SE) 2016-11-29 US disclosed
CN-103694195-B Aromatic heterocyclic small molecular organic compounds and derivative, preparation method and medicinal use EAST CHINA NORMAL UNIVERSITY (CN) 2016-04-06 CN disclosed
EP-2997824-A1 NOVEL HERBICIDES Syngenta Participations AG. (CH) 2016-03-23 EP disclosed
CN-105164121-A Perfluorinated cyclopropyl-fused 1, 3-oxazin-2-amine compounds as beta-secretase inhibitors and methods of use thereof AMGEN INC 2015-12-16 CN disclosed
EP-2375898-B1 NOVEL HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2015-09-16 EP disclosed
CN-104817553-A Aryl-heterocycle substituted pyrimidinediamine compound and its derivative and pharmaceutical use thereof UNIV EAST CHINA NORMAL 2015-08-05 CN disclosed
WO-2000058373-A1 PROCESS FOR PRODUCING POLYOLEFINS EASTMAN CHEMICAL COMPANY (US) 2000-10-05 WO disclosed
WO-2000052069-A1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEMICAL COMPANY (US) 2000-09-08 WO disclosed
WO-2000052068-A1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEMICAL COMPANY (US) 2000-09-08 WO disclosed
WO-2000052067-A1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEMICAL COMPANY (US) 2000-09-08 WO disclosed
EP-0253390-B1 PHOTOGRAPHIC SUPPORT AND COLOR PHOTOSENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1992-12-02 EP disclosed
US-4894321-A SILVER HALIDE EMULSIONS, IMAGES, MULTILAYER FUJI PHOTO FILM CO., LTD. (JP) 1990-01-16 US disclosed
US-4851327-A THIN SOLID METAL FILM FUJI PHOTO FILM CO., LTD. (JP) 1989-07-25 US disclosed
EP-0253390-A2 Photographic support and color photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1988-01-20 EP disclosed
US-4585472-A PRE- AND POSTEMERGENCE HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1986-04-29 US disclosed