Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 5/20 | 0.40 |
| ▸ | TACR1 | P25103 | 8/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4490431 | 0.69 | CETP (0.40) | CETPTACR1 | |
| SCHEMBL4500123 | 0.68 | CETP (0.35) | CETPGPBAR1 | |
| SCHEMBL4503976 | 0.67 | CETP (0.42) | CETPTACR1MEN1KMT2AGPBAR1 | |
| SCHEMBL3829886 | 0.66 | CETP (0.45) | CETPTACR1GPBAR1 | |
| SCHEMBL129360 | 0.65 | CETP (0.47) | CETPTACR1GPBAR1 | |
| SCHEMBL14908874 | 0.64 | TSHR (0.42) | MEN1KMT2A | |
| SCHEMBL1587890 | 0.64 | CETP (0.44) | CETPTACR1GPBAR1 | |
| SCHEMBL1587844 | 0.63 | SLC6A4 (0.43) | CETPGPBAR1 | |
| SCHEMBL14309719 | 0.62 | CETP (0.64) | CETP | |
| SCHEMBL14311416 | 0.62 | CETP (0.64) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023729-A1 | Trisubstituted amine compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023729-A1 | Trisubstituted amine compound | CETP, MTTP, APOB | CETP 1/4885TACR1 3300/4885MEN1 2338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.