Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.65 |
| ▸ | CES1 | P23141 | 4/20 | 0.65 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.62 |
| ▸ | PPARG | P37231 | 7/20 | 0.62 |
| ▸ | PPARD | Q03181 | 7/20 | 0.62 |
| ▸ | PPARA | Q07869 | 7/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.62 |
| ▸ | TSHR | P16473 | 5/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | TLR2 | O60603 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | FABP4 | P15090 | 2/20 | 0.62 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.62 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | PDE4A | P27815 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL79563 | 1.00 | CES2 (0.65) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL56011 | 1.00 | CES2 (0.65) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL155222 | 1.00 | — | — | |
| SCHEMBL160220 | 1.00 | CES2 (0.65) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL4141832 | 1.00 | CES2 (0.65) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL54806 | 1.00 | CES2 (0.65) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL421576 | 1.00 | CES2 (0.65) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL41461 | 1.00 | CES2 (0.65) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL276881 | 1.00 | CES2 (0.65) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL205397 | 1.00 | CES2 (0.65) | CES2CES1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 396 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206446-B1 | CARBOXYLIC ACID AMIDES, THEIR PRODUCTION AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-05-26 | — | — | EP | claimed |
| WO-2023190166-A1 | CATIONIC LIPID HAVING DISULFIDE BOND, LIPID MEMBRANE STRUCTURE INCLUDING SAME, NUCLEIC ACID INTRODUCTION AGENT AND PHARMACEUTICAL COMPOSITION CONTAINING ANY ONE OF SAME, METHOD FOR INTRODUCING NUCLEIC ACID INTO CELL OR TARGET CELL, AND METHOD FOR PRODUCING CELLULAR PHARMACEUTICAL | 日油株式会社 | 2023-10-05 | — | — | WO | disclosed |
| WO-2023190170-A1 | METHOD FOR PRODUCING NUCLEIC ACID-ENCAPSULATED LIPID NANOPARTICLES, METHOD FOR PRODUCING PHARMACEUTICAL COMPOSITION CONTAINING SAID LIPID NANOPARTICLES, AND METHOD FOR INTRODUCING NUCLEIC ACID INTO CELL OR TARGET CELL | 日油株式会社 | 2023-10-05 | — | — | WO | disclosed |
| EP-2883865-B1 | Compound capable of binding S1P receptor and pharmaceutical use thereof | ONO PHARMACEUTICAL CO (JP) | 2019-09-25 | — | — | EP | disclosed |
| US-10202383-B2 | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-02-12 | — | — | US | disclosed |
| US-20180291025-A1 | 8-[3-AMINO-PIPERIDIN-1-YL]-XANTHINES, THE PREPARATION THEREOF AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INT (DE) | 2018-10-11 | — | — | US | disclosed |
| US-10023574-B2 | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-07-17 | — | — | US | disclosed |
| US-20180057495-A1 | 8-[3-AMINO-PIPERIDIN-1-YL]-XANTHINES, THE PREPARATION THEREOF AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INT (DE) | 2018-03-01 | — | — | US | disclosed |
| US-20170362381-A1 | THERMALLY STABLE ALIGNMENT MATERIALS | ROLIC AG (CH) | 2017-12-21 | — | — | US | disclosed |
| CN-103718109-B | Photosensitive polymer combination and film, pattern forming material, polyimide film, relief pattern and preparation method and semiconductor device | 富士胶片株式会社 | 2017-06-23 | — | — | CN | disclosed |
| EP-0088046-A2 | Lipids in the aqueous phase | CIBA-GEIGY AG (CH) | 1983-09-07 | — | — | EP | disclosed |
| US-4346165-A | INCORPORATING METAL COMPLEX AND SPECIFIC DISCOLORATION INHIBITION AID | FUJI PHOTO FILM CO., LTD. (JP) | 1982-08-24 | — | — | US | disclosed |
| US-4343886-A | Method for stabilizing dye images in color photographic sensitive materials using a ligand as a dye image stabilizer precursor in combination with metal ions | FUJI PHOTO FILM CO., LTD. (JP) | 1982-08-10 | — | — | US | disclosed |
| US-4269926-A | A SUPPORT HAVING A MORDANT LAYER CONTAINING A HALOMETAL COMPLEX OF A 2-((2-MERCAPTO PHENYL)IMINO) PYRIDINE | FUJI PHOTO FILM CO., LTD. (JP) | 1981-05-26 | — | — | US | disclosed |
| US-4268605-A | Stabilization of organic substrate materials including photographic dye images against the action of light | FUJI PHOTO FILM CO., LTD. (JP) | 1981-05-19 | — | — | US | disclosed |
| US-4254195-A | BY ADDITION OF A COMPLEX METAL COMPOUND IN ASSOCIATION WITH THE SUBSTRATE | FUJI PHOTO FILM CO., LTD. (JP) | 1981-03-03 | — | — | US | disclosed |
| US-4246330-A | METAL COMPLEX SALT COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1981-01-20 | — | — | US | disclosed |
| US-4245018-A | CHELATES OF COPPER, COBALT, NICKEL, PALLADIUM, OR PLATINUM | FUJI PHOTO FILM CO., LTD. (JP) | 1981-01-13 | — | — | US | disclosed |
| US-4242429-A | METAL COMPLEXES OF N,N'-BIS(2-MERCAPTOPHENYL)-DIIMINE | FUJI PHOTO FILM CO., LTD. (JP) | 1980-12-30 | — | — | US | disclosed |
| US-4239851-A | DISSOLVING AN OIL SOLUBLE ADDITIVE IN AN EPOXY COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1980-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10202383-B2 | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions | DPP8, DPP4, DPP3 | CES2 387/4885CES1 275/4885GPR84 1164/4885 |
| US-20180057495-A1 | 8-[3-AMINO-PIPERIDIN-1-YL]-XANTHINES, THE PREPARATION THEREOF AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | DPP8, DPP4, DPP3 | CES2 387/4885CES1 275/4885GPR84 1164/4885 |
| US-20180291025-A1 | 8-[3-AMINO-PIPERIDIN-1-YL]-XANTHINES, THE PREPARATION THEREOF AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | DPP8, DPP4, DPP3 | CES2 387/4885CES1 275/4885GPR84 1164/4885 |
| US-10023574-B2 | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions | DPP8, DPP4, DPP3 | CES2 387/4885CES1 275/4885GPR84 1164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.