Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 9/20 | 0.52 |
| ▸ | ACE | P12821 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 2/20 | 0.36 |
| ▸ | CPB1 | P15086 | 4/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6488008 | 0.89 | CPB2 (0.50) | CPB2ACEPOLBNAMPTCPA1 | |
| SCHEMBL4502124 | 0.83 | CPB2 (0.48) | CPB2ACENAMPT | |
| SCHEMBL4515230 | 0.82 | CPB2 (0.57) | CPB2ACECPB1 | |
| SCHEMBL4521167 | 0.82 | CPB2 (0.57) | CPB2ACECPA1CPB1 | |
| SCHEMBL4509144 | 0.82 | CPB2 (0.46) | CPB2ACENAMPTCPA1CPB1 | |
| SCHEMBL4009042 | 0.82 | CPB2 (0.64) | CPB2ACECPA1CPB1 | |
| SCHEMBL4508225 | 0.81 | CPB2 (0.56) | CPB2ACECPA1CPB1 | |
| SCHEMBL4512112 | 0.81 | CPB2 (0.56) | CPB2ACECPA1CPB1 | |
| SCHEMBL4512159 | 0.81 | CPB2 (0.60) | CPB2ACECPA1CPB1 | |
| SCHEMBL4493363 | 0.81 | CPB2 (0.55) | CPB2ACECPA1CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572817-B2 | 2,5-disubstituted 3-mercaptopentanoic acid | ASTRAZENECA AB (SE) | 2009-08-11 | — | — | US | claimed |
| US-7572817-B2 | 2,5-disubstituted 3-mercaptopentanoic acid | ASTRAZENECA AB (SE) | 2009-08-11 | — | — | US | disclosed |
| EP-1532111-B1 | 2,5-DISUBSTITUTED 3-MERCAPTOPENTANOIC ACID | ASTRAZENECA AB (SE) | 2007-08-08 | — | — | EP | disclosed |
| EP-1532111-A1 | 2,5-DISUBSTITUTED 3-MERCAPTOPENTANOIC ACID | AstraZeneca AB (SE) | 2005-05-25 | — | — | EP | disclosed |
| WO-2003106420-A1 | 2,5-DISUBSTITUTED 3-MERCAPTOPENTANOIC ACID | ASTRAZENECA AB (SE) | 2003-12-24 | — | — | WO | disclosed |