SCHEMBL450703

SCHEMBL450703

CCCCC(CC)COC(=O)C(=CC(=O)O)CC(CC)CCCC

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
CYP3A4 P08684 5/20 0.51
TDP1 Q9NUW8 2/20 0.51
ATM Q13315 1/20 0.51
RECQL P46063 1/20 0.47
ALDH1A1 P00352 6/20 0.46
CA2 P00918 4/20 0.46
LMNA P02545 3/20 0.45
MAPK1 P28482 3/20 0.45
HSD17B10 Q99714 1/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MMP9 P14780 1/20 0.36
MMP8 P22894 1/20 0.36
MMP14 P50281 1/20 0.36
CA1 P00915 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22115516 0.90 TSHR (0.54) TSHRCYP3A4TDP1ATMRECQL
SCHEMBL27619467 0.90 TSHR (0.43) TSHRCYP3A4TDP1ATMRECQL
SCHEMBL2205096 0.84 TSHR (0.38) TSHRCYP3A4TDP1ATMRECQL
SCHEMBL27886573 0.83 TSHR (0.52) TSHRCYP3A4TDP1ATMRECQL
SCHEMBL30853653 0.83 TSHR (0.53) TSHRCYP3A4TDP1ATMRECQL
SCHEMBL29558890 0.82 TSHR (0.55) TSHRCYP3A4TDP1ATMRECQL
SCHEMBL29557819 0.82 TSHR (0.55) TSHRCYP3A4TDP1ATMRECQL
SCHEMBL9709283 0.82 TSHR (0.37) TSHRCYP3A4TDP1ATMRECQL
SCHEMBL2250221 0.82 CA2 (0.43) TSHRCYP3A4TDP1ATMRECQL
SCHEMBL183765 0.82 CA2 (0.43) TSHRCYP3A4TDP1ATMRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0442983-B1 EMULSION PRESSURE-SENSITIVE ADHESIVE POLYMERS EXHIBITING EXCELLENT ROOM- AND LOW-TEMPERATURE PERFORMANCE AVERY DENNISON CORP (US) 1994-04-20 EP claimed
EP-2614096-B1 ADHESIVE SYSTEM, METHOD OF ASSEMBLY OF DISTINCT COMPONENTS THEREWITH TEKNOR APEX CO (US) 2018-12-05 EP disclosed
US-8871864-B2 Adhesive system, method of assembly of distinct components therewith TEKNOR APEX COMPANY (US) 2014-10-28 US disclosed
EP-2614096-A1 ADHESIVE SYSTEM, METHOD OF ASSEMBLY OF DISTINCT COMPONENTS THEREWITH Teknor Apex Company (US) 2013-07-17 EP disclosed
US-20120064356-A1 Adhesive system, method of assembly of distinct components therewith TEKNOR APEX COMPANY (US) 2012-03-15 US disclosed
WO-2012033520-A1 ADHESIVE SYSTEM, METHOD OF ASSEMBLY OF DISTINCT COMPONENTS THEREWITH TEKNOR APEX COMPANY (US) 2012-03-15 WO disclosed
US-7981932-B2 Salts of alkyl esters of sulfonated dicarboxylic acids and compositions containing same COGNIS IP MANAGEMENT GMBH (DE) 2011-07-19 US disclosed
US-20070214999-A1 Salts of alkyl esters of sulfonated dicarboxylic acids and compositions containing same COGNIS IP MANAGEMENT GMBH (DE) 2007-09-20 US disclosed
US-6583250-B2 Particularly to cyanoacrylate adhesives, by mixing in a polymerization initiator capable of initiating polymerization of the monomers of the adhesive, at a temperature above the polyolefin's glass transition temperature HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-06-24 US disclosed
US-20010009954-A1 POLYOLEFINE MATERIALS WITH IMPROVED ADHESIVITY COGNIS DEUTSCHLAND GMBH & CO. KG (DE) 2001-07-26 US disclosed
US-4339530-A Developer mixture for developing exposed light-sensistive copying layers HOECHST AKTIENGESELLSCHAFT (DE) 1982-07-13 US disclosed
US-4277592-A SOLUTION POLYMERIZATION IN ALIPHATIC HYDROCARBON USING TWO TYPES OF CATALYST, ONE OF WHICH IS SOLUBLE AND ONE OF WHICH IS INSOLUBLE HOECHST AKTIENGESELLSCHAFT (DE) 1981-07-07 US disclosed
US-4093791-A Process for suspension polymerization of vinyl chloride with molecular oxygen WACKER-CHEMIE GMBH (DT) 1978-06-06 US disclosed