Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29442430 | 0.81 | HTT (0.49) | TP53HTTFOLH1MRGPRX4CLCN2 | |
| SCHEMBL113974 | 0.81 | HTT (0.49) | TP53HTTFOLH1MRGPRX4CLCN2 | |
| SCHEMBL23453516 | 0.79 | TP53 (0.59) | TP53HTTFOLH1MRGPRX4CLCN2 | |
| SCHEMBL1982031 | 0.76 | HTT (0.50) | TP53HTTFOLH1MRGPRX4CLCN2 | |
| SCHEMBL12164265 | 0.76 | KDM4E (0.55) | TP53HTTFOLH1MRGPRX4CLCN2 | |
| SCHEMBL28857874 | 0.73 | HTT (0.50) | TP53HTTFOLH1MRGPRX4CLCN2 | |
| SCHEMBL6043415 | 0.73 | TP53 (0.50) | TP53HTTFOLH1MRGPRX4CLCN2 | |
| SCHEMBL7808887 | 0.73 | TP53 (0.47) | TP53HTTFOLH1MRGPRX4CLCN2 | |
| SCHEMBL3175790 | 0.73 | HTT (0.53) | TP53HTTFOLH1MRGPRX4CLCN2 | |
| SCHEMBL8791191 | 0.73 | ALDH1A1 (0.56) | TP53HTTFOLH1MRGPRX4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022178428-A9 | TARGETED BIFUNCTIONAL DEGRADERS AND METHODS USING SAME | YALE UNIVERSITY (US) | 2023-08-17 | — | — | WO | disclosed |
| WO-2012002913-A1 | PROCESS OF FORMING A CYCLIC IMIDE | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-01-05 | — | — | WO | disclosed |