Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.59 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.59 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL4743691 | 1.00 | OR51E2 (0.59) | OR51E2GLRA1SLC6A9LMNAALDH1A1 | |
| Glycerin SCHEMBL8821885 | 0.92 | OR51E2 (0.50) | OR51E2GLRA1SLC6A9LMNAALDH1A1 | |
| Glycerin SCHEMBL8603392 | 0.90 | OR51E2 (0.48) | OR51E2GLRA1SLC6A9LMNAALDH1A1 | |
| Glycerin SCHEMBL28921585 | 0.90 | OR51E2 (0.48) | OR51E2GLRA1SLC6A9LMNAALDH1A1 | |
| Mannitol SCHEMBL9400683 | 0.88 | USP2 (0.54) | OR51E2GLRA1SLC6A9LMNAALDH1A1 | |
| Glycine SCHEMBL27738847 | 0.85 | OR51E2 (0.48) | OR51E2GLRA1SLC6A9LMNAALDH1A1 | |
| Glycerin SCHEMBL9668067 | 0.84 | OR51E2 (0.42) | OR51E2GLRA1SLC6A9LMNAALDH1A1 | |
| Thiodiglycol SCHEMBL1560878 | 0.84 | TDP1 (0.42) | OR51E2GLRA1SLC6A9LMNAALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL11664911 | 0.84 | TSHR (0.42) | OR51E2GLRA1SLC6A9LMNAALDH1A1 | |
| Alanine SCHEMBL15323960 | 0.82 | OR51E2 (0.40) | OR51E2GLRA1SLC6A9LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 385 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805528-A | Cystine knot scaffold platform | 豪夫迈·罗氏有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-114591422-A | Cystine knot scaffold platform | 豪夫迈·罗氏有限公司 | 2022-06-07 | — | — | CN | claimed |
| CN-111187857-A | Primer pair, kit and preparation method and application of kit for detecting novel coronavirus through isothermal amplification | 深圳市芯思微生物科技有限公司 | 2020-05-22 | — | — | CN | claimed |
| EP-1991200-B1 | FLUOROQUINOLONE COMPOSITIONS | IDEXX LAB INC (US) | 2018-05-23 | — | — | EP | claimed |
| CN-108026162-A | Cystine knot scaffold platform | 豪夫迈·罗氏有限公司 | 2018-05-11 | — | — | CN | claimed |
| CN-104428014-A | Biocompatible hydrogel treatment for retinal detachment | MEDICUS BIOSCIENCES LLC | 2015-03-18 | — | — | CN | claimed |
| CN-103651332-A | Docosahexaenoic acid-glycine-glycerinum compound human seminal fluid cryoprotectant and preparation method thereof | GUANGDONG FAMILY PLANNING RES INST | 2014-03-26 | — | — | CN | claimed |
| CN-114591422-B | Cystine knot support platform | 豪夫迈·罗氏有限公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024028558-A1 | ENZYMATICALLY PRODUCED GLUCOSYLATED MYCOSPORINES FOR DEVELOPING INNOVATIVE ANTI-UV PRODUCTS | Université de Pau et du Pays de l'Adour (FR) | 2024-02-08 | — | — | WO | disclosed |
| US-11891590-B2 | Detergent for corneum-derived stains, and method for evaluating ability to degrade corneum-derived stains | KAO CORPORATION (JP) | 2024-02-06 | — | — | US | disclosed |
| WO-2024024527-A1 | MUTANT PROTEASE | 花王株式会社 | 2024-02-01 | — | — | WO | disclosed |
| EP-3470517-B1 | ALKALINE PROTEASE VARIANT | KAO CORP (JP) | 2024-01-10 | — | — | EP | disclosed |
| WO-2023220337-A1 | ALTERNATIVE FIBERS AND MICRO-FIBRILLATED CELLULOSE COATED PACKAGING PAPERS, AND FILMS AND SUBSTRATES | WM. WRIGLEY JR. COMPANY (US) | 2023-11-16 | — | — | WO | disclosed |
| US-4558009-A | NOCARDIA | ELI LILLY AND COMPANY (US) | 1985-12-10 | — | — | US | disclosed |
| US-4495179-A | DEMETHYLVANCOMYCIN; GRAM POSITIVE ANTIBACTERIAL AGENT | ELI LILLY AND COMPANY (US) | 1985-01-22 | — | — | US | disclosed |
| US-4013510-A | Glycoside-hydrolase enzyme inhibitors | FARBENFABRIKEN BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-22 | — | — | US | disclosed |
| US-4006068-A | CURABLE | THE DOW CHEMICAL COMPANY (US) | 1977-02-01 | — | — | US | disclosed |
| US-3951745-A | CULTURING OF ACTINOMYCETALES | FARBENFABRIKEN BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
| US-3935269-A | Copolymers of N-substituted aziridines and epoxides episulfides | THE DOW CHEMICAL COMPANY (US) | 1976-01-27 | — | — | US | disclosed |
| US-3934006-A | ADIPOSITY, ATHEROSCLEROSIS, DIABETES, CARIES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | disclosed |