Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL1130667 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL5083626 | 0.94 | MEN1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL7915242 | 0.92 | SMN1; SMN2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL5077691 | 0.91 | MEN1 (0.41) | — | |
| Hydrochloric Acid SCHEMBL6553917 | 0.91 | PPIA (0.33) | — | |
| Hydrochloric Acid SCHEMBL5084265 | 0.91 | MEN1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL7991412 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL5081161 | 0.91 | HTT (0.31) | — | |
| Hydrochloric Acid SCHEMBL18280794 | 0.90 | MEN1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL6553489 | 0.88 | MYC (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 642 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242745-A1 | Process for Production of Thermoplastic Vulcanizates using Supported Catalyst Systems and Compositions Made Therefrom | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2023-08-03 | — | — | US | claimed |
| WO-2023051575-A1 | CATALYST COMPOSITION AND APPLICATION THEREOF | 中国石油化工股份有限公司 | 2023-04-06 | — | — | WO | claimed |
| US-20180244812-A1 | Spherical Supported Transition Metal Catalyst | PETROCHINA COMPANY LIMITED (CN) | 2018-08-30 | — | — | US | claimed |
| EP-2516598-B1 | PROCESS FOR PRODUCING NOVEL SYNTHETIC BASESTOCKS | EXXONMOBIL CHEM PATENTS INC (US) | 2016-06-29 | — | — | EP | claimed |
| US-9115229-B2 | Particulate metallocene-alumoxane catalyst | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2015-08-25 | — | — | US | claimed |
| US-20140213834-A1 | ULTRA HIGH VISCOSITY SYNTHETIC BASE STOCKS AND PROCESSES FOR PREPARING SAME | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2014-07-31 | — | — | US | claimed |
| US-20140213743-A1 | Particulate Metallocene-Alumoxane Catalyst | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2014-07-31 | — | — | US | claimed |
| US-8722567-B2 | Particulate metallocene-alumoxane catalyst | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2014-05-13 | — | — | US | claimed |
| US-20140045681-A1 | Particulate Metallocene-Alumoxane Catalyst | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2014-02-13 | — | — | US | claimed |
| EP-1910431-B1 | POLYALPHA-OLEFIN COMPOSITIONS AND PROCESSES TO PRODUCE THE SAME | EXXONMOBIL CHEM PATENTS INC (US) | 2013-11-27 | — | — | EP | claimed |
| US-5627245-A | Process for the preparation of a syndiotactic propylene copolymer | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-06 | — | — | US | claimed |
| US-5587501-A | Process for the preparation of syndiotactic polyolefins having a broad molecular weight distribution | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-24 | — | — | US | claimed |
| US-5545829-A | Process for preparing cycloolefin copolymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-13 | — | — | US | claimed |
| US-5539066-A | Process for the preparation of syndiotactic polyolefins having a broad molecular weight distribution | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-23 | — | — | US | claimed |
| EP-0516019-B1 | Process for preparing syndiotactic polyolefins with large molecular weight distribution | HOECHST AG (DE) | 1995-12-27 | — | — | EP | claimed |
| EP-0659773-A1 | Production of polyolefins containing long chain branches by a gas phase process | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-06-28 | — | — | EP | claimed |
| EP-0387690-B1 | Process for preparing a syndiotactic polyolefin | HOECHST AG (DE) | 1995-06-28 | — | — | EP | claimed |
| US-5422409-A | Stopping polymerization when molecular weight distribution Mw/Mn is less than 2 | HOECHST AKTIENGESELLSCHAFT | 1995-06-06 | — | — | US | claimed |
| EP-0572990-A2 | Method for preparing ethylene copolymer | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-12-08 | — | — | EP | claimed |
| US-5232993-A | Homo and copolymerization of propylene in two stages, in the presence of a catalyst having a transition metal component and an organoaluminum compound. | HOECHST AG (DE) | 1993-08-03 | — | — | US | claimed |