Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 3/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.43 |
| ▸ | BBOX1 | O75936 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1063585 | 1.00 | FTO (0.47) | FTOEGLN1BBOX1CA12CA1 | |
| Trifluoroacetic Acid SCHEMBL1063590 | 1.00 | FTO (0.47) | FTOEGLN1BBOX1CA12CA1 | |
| Trifluoroacetic Acid SCHEMBL1061191 | 0.97 | FTO (0.47) | FTOEGLN1BBOX1CA12CA1 | |
| Trifluoroacetic Acid SCHEMBL1061194 | 0.97 | FTO (0.47) | FTOEGLN1BBOX1CA12CA1 | |
| Trifluoroacetic Acid SCHEMBL4501208 | 0.97 | FTO (0.47) | FTOEGLN1BBOX1CA12CA1 | |
| SCHEMBL524055 | 0.96 | FTO (0.48) | FTOEGLN1BBOX1THRATHRB | |
| SCHEMBL522586 | 0.96 | FTO (0.48) | FTOEGLN1BBOX1THRATHRB | |
| SCHEMBL522587 | 0.96 | FTO (0.48) | FTOEGLN1BBOX1THRATHRB | |
| SCHEMBL523146 | 0.92 | FTO (0.48) | FTOEGLN1BBOX1THRATHRB | |
| SCHEMBL522235 | 0.92 | FTO (0.48) | FTOEGLN1BBOX1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629357-B2 | Antihypoxic agents; adjust concentration of erythropoietin concentration in blood; strokes; antiepileptic agents; neurodegenerative disease ; liver disorders; antiischemic agents | FIBROGEN, INC. (US) | 2009-12-08 | — | — | US | claimed |
| CN-101242817-B | HIF1 alpha modulators purposes in treatment cancer | 菲布罗根公司 | 2016-08-31 | — | — | CN | disclosed |