Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 2/20 | 0.77 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.77 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.77 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 3/20 | 0.35 |
| ▸ | LIPC | P11150 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4512245 | 1.00 | PRKD3 (0.77) | PRKD3PRKD1PRKD2PRKCIPRMT5 | |
| SCHEMBL4512250 | 1.00 | PRKD3 (0.77) | PRKD3PRKD1PRKD2PRKCIPRMT5 | |
| SCHEMBL4514713 | 0.87 | PRKD3 (1.00) | PRKD3PRKD1PRKD2GSK3BDYRK1A | |
| SCHEMBL4514725 | 0.87 | PRKD3 (1.00) | PRKD3PRKD1PRKD2GSK3BDYRK1A | |
| SCHEMBL4514722 | 0.87 | PRKD3 (1.00) | PRKD3PRKD1PRKD2GSK3BDYRK1A | |
| SCHEMBL4512734 | 0.87 | PRKD3 (0.74) | PRKD3PRKD1PRKD2PIK3CAMAPK1 | |
| SCHEMBL4512731 | 0.87 | PRKD3 (0.74) | PRKD3PRKD1PRKD2PIK3CAMAPK1 | |
| SCHEMBL4512723 | 0.87 | PRKD3 (0.74) | PRKD3PRKD1PRKD2PIK3CAMAPK1 | |
| Hydrochloric Acid SCHEMBL29565702 | 0.86 | PRKD3 (0.98) | PRKD3PRKD1PRKD2GSK3BDYRK1A | |
| SCHEMBL4511350 | 0.82 | PRKD3 (0.74) | PRKD3PRKD1PRKD2MAPK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247519-A1 | AMINO-ETHYL-AMINO-ARYL (AEAA) COMPOUNDS AND THEIR USE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-10-01 | — | — | US | disclosed |
| US-20090247519-A1 | AMINO-ETHYL-AMINO-ARYL (AEAA) COMPOUNDS AND THEIR USE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-10-01 | — | — | US | disclosed |
| WO-2007125331-A2 | AMINO-ETHYL-AMINO-ARYL (AEAA) COMPOUNDS AND THEIR USE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2007-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247519-A1 | AMINO-ETHYL-AMINO-ARYL (AEAA) COMPOUNDS AND THEIR USE | PKD2, PKD1, AADAT | PRKD3 9/4885PRKD1 49/4885PRKD2 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.