SCHEMBL4512360

SCHEMBL4512360

C=C(C)C(=O)OCCC(C)(C)[SiH2]C

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.47
TSHR P16473 3/20 0.46
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 2/20 0.37
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3393774 0.86 THRB (0.44) THRBTSHRPOLBAPEX1HTT
SCHEMBL27755583 0.84 THRB (0.46) THRBTSHRPOLBAPEX1HTT
SCHEMBL8965485 0.80 THRB (0.53) THRBTSHRPOLBAPEX1HTT
SCHEMBL438464 0.80 THRB (0.53) THRBTSHRPOLBAPEX1HTT
SCHEMBL736884 0.79 THRB (0.44) THRBTSHRPOLBAPEX1HTT
SCHEMBL3688925 0.79 THRB (0.52) THRBTSHRPOLBAPEX1HTT
SCHEMBL22686158 0.79 THRB (0.52) THRBTSHRPOLBAPEX1HTT
SCHEMBL18051644 0.79 THRB (0.52) THRBTSHRPOLBAPEX1HTT
Fluoride SCHEMBL28255974 0.79 THRB (0.52) THRBTSHRPOLBAPEX1HTT
SCHEMBL26002227 0.78 THRB (0.55) THRBTSHRPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7615594-B2 Graft copolymers and impact-resistant flame-retardant resin compositions containing the same KANEKA CORPORATION (JP) 2009-11-10 US disclosed
EP-1964888-A1 Graft copolymers and impact-resistant, flame-retardant resin compositions containing same Kaneka Corporation (JP) 2008-09-03 EP disclosed
US-20050038149-A1 Graft copolymers and impact-resistant flame-retardant resin compositions containing the same KANEKA CORPORATION (JP) 2005-02-17 US disclosed
EP-1475396-A1 GRAFT COPOLYMERS AND IMPACT-RESISTANT FLAME-RETARDANT RESIN COMPOSITIONS CONTAINING THE SAME KANEKA CORPORATION (JP) 2004-11-10 EP disclosed