Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.55 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8268103 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HTTKMT2AMEN1EPHX1 | |
| SCHEMBL3196481 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HTTKMT2AMEN1EPHX1 | |
| SCHEMBL29757862 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HTTKMT2AMEN1EPHX1 | |
| SCHEMBL29757861 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HTTKMT2AMEN1EPHX1 | |
| SCHEMBL6724993 | 0.83 | HTT (0.63) | ALDH1A1HTTKMT2AMEN1EPHX1 | |
| SCHEMBL10814631 | 0.81 | HTT (0.60) | ALDH1A1HTTKMT2AMEN1EPHX1 | |
| SCHEMBL1568062 | 0.79 | KMT2A (0.71) | ALDH1A1HTTKMT2AMEN1EPHX1 | |
| SCHEMBL9011724 | 0.79 | HTT (0.75) | ALDH1A1HTTKMT2AMEN1EPHX1 | |
| SCHEMBL3210483 | 0.78 | ALDH1A1 (0.72) | ALDH1A1HTTKMT2AMEN1EPHX1 | |
| SCHEMBL11746751 | 0.78 | ALDH1A1 (0.72) | ALDH1A1HTTKMT2AMEN1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233960-A1 | Kinase Inhibitors | DEVGEN NV (BE) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233960-A1 | Kinase Inhibitors | ROCK1, MAP3K1, MAP3K11 | ALDH1A1 2810/4885HTT 1131/4885KMT2A 3194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.