Sugi Predict

Sugi Predict / Compounds / SCHEMBL451290

SCHEMBL451290

SCHEMBL451290

c1ccc(-c2ccnc3c2ccc2cccnc23)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CCR1 P32246 5/20 0.59
▸ CCR8 P51685 5/20 0.59
▸ CCR5 P51681 3/20 0.59
▸ L3MBTL1 Q9Y468 2/20 0.59
▸ LMNA P02545 3/20 0.57
▸ KDM4E B2RXH2 2/20 0.57
▸ MAPT P10636 2/20 0.57
▸ GMNN O75496 1/20 0.57
▸ TP53 P04637 1/20 0.57
▸ HSP90AA1 P07900 1/20 0.57
▸ MMP2 P08253 1/20 0.57
▸ CYP3A4 P08684 1/20 0.57
▸ CYP2D6 P10635 1/20 0.57
▸ MMP9 P14780 1/20 0.57
▸ ALOX15 P16050 1/20 0.57
▸ TSHR P16473 1/20 0.57
▸ NFKB1 P19838 1/20 0.57
▸ MMP8 P22894 1/20 0.57
▸ THPO P40225 1/20 0.57
▸ MTOR P42345 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30287028 1.00 CCR1 (0.59) CCR1CCR8CCR5L3MBTL1LMNA
Phenanthroline SCHEMBL10705881 1.00 CCR1 (0.59) CCR1CCR8CCR5L3MBTL1LMNA
SCHEMBL22362606 0.98 CCR1 (0.57) CCR1CCR8CCR5L3MBTL1LMNA
SCHEMBL1701024 0.97 CCR1 (0.56) CCR1CCR8CCR5L3MBTL1LMNA
SCHEMBL20713733 0.92 CCR1 (0.51) CCR1CCR8CCR5L3MBTL1LMNA
SCHEMBL20726743 0.92 CCR1 (0.51) CCR1CCR8CCR5L3MBTL1LMNA
SCHEMBL24654494 0.91 CCR1 (0.50) CCR1CCR8CCR5L3MBTL1LMNA
SCHEMBL20726767 0.91 CCR1 (0.50) CCR1CCR8CCR5L3MBTL1LMNA
Naphthalene SCHEMBL29241630 0.91 PRKACA (0.49) CCR1CCR8CCR5L3MBTL1LMNA
SCHEMBL28868 0.89 IKBKB (0.53) CCR1CCR8CCR5L3MBTL1TOP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108440448-B Synthesis method of 3-phenyl-1, 2, 4-benzothiadiazine-1, 1(2H) -dioxide compound 温州大学苍南研究院 2021-08-24 — — CN claimed
CN-108314649-B Synthetic method of 6-phenylphenanthridine compound 温州大学 2021-03-19 — — CN claimed
CN-109713026-A A kind of silicon substrate electroluminescence display panel and its manufacturing method, display device 京东方科技集团股份有限公司 2019-05-03 — — CN claimed
CN-117567668-A Iron removal adsorption resin, preparation method thereof and iron removal method of lithium battery recovery liquid 江苏海普功能材料有限公司 2024-02-20 — — CN disclosed
US-20230292595-A1 Organic Light Emitting Diode and Device Comprising the Same NOVALED GMBH (DE) 2023-09-14 — — US disclosed
US-20230292595-A1 Organic Light Emitting Diode and Device Comprising the Same NOVALED GMBH (DE) 2023-09-14 — — US disclosed
EP-4234539-A1 ORGANIC MATERIAL FOR AN ELECTRONIC OPTOELECTRONIC DEVICE AND ELECTRONIC DEVICE COMPRISING THE ORGANIC MATERIAL Novaled GmbH (DE) 2023-08-30 — — EP disclosed
US-20230270004-A1 Organic Light Emitting Diode and Device Comprising the Same NOVALED GMBH (DE) 2023-08-24 — — US disclosed
US-20230270004-A1 Organic Light Emitting Diode and Device Comprising the Same NOVALED GMBH (DE) 2023-08-24 — — US disclosed
US-20230146030-A1 ARYLAMINE COMPOUND, ELECTRONIC COMPONENT USING SAME AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-05-11 — — US disclosed
US-20230146030-A1 ARYLAMINE COMPOUND, ELECTRONIC COMPONENT USING SAME AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-05-11 — — US disclosed
EP-2669967-A1 Electronic device including phenanthroline derivative E. I. du Pont de Nemours and Company (US) 2013-12-04 — — EP disclosed
US-8436341-B2 Electronic device including phenanthroline derivative E I DU PONT DE NEMOURS AND COMPANY (US) 2013-05-07 — — US disclosed
US-8309731-B2 Electronic device including phenanthroline derivative E I DU PONT DE NEMOURS AND COMPANY (US) 2012-11-13 — — US disclosed
US-20120065402-A1 ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE E.I.DU PONT DE NEMOURS AND COMPANY (US) 2012-03-15 — — US disclosed
EP-2361009-A2 ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE E. I. du Pont de Nemours and Company (US) 2011-08-31 — — EP disclosed
US-20110151586-A1 POLYMER ENCAPSULATED PARTICLES AS SURFACE ENHANCED RAMAN SCATTERING PROBES Nanyang Technological Yniversity 2011-06-23 — — US disclosed
US-20100207108-A1 ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-08-19 — — US disclosed
WO-2010075379-A2 ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-01 — — WO disclosed
WO-2009142604-A1 POLYMER ENCAPSULATED PARTICLES AS SURFACE ENHANCED RAMAN SCATTERING PROBES NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2009-11-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120065402-A1 ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE PAH, AHR, TYR CCR1 3123/4885CCR8 3729/4885CCR5 3758/4885
US-20230146030-A1 ARYLAMINE COMPOUND, ELECTRONIC COMPONENT USING SAME AND ELECTRONIC DEVICE OCIAD2, AOC2, OCIAD1 CCR1 3860/4885CCR8 3301/4885CCR5 3585/4885
US-20100207108-A1 ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE PAH, AHR, TYR CCR1 3200/4885CCR8 3719/4885CCR5 3605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.